BACKGROUND: Preoperative diagnosis of lymph node metastasis is often difficult. A number of different criteria have been advocated in the literature, however, an optimal criterion has not yet been determined in patients with rectal carcinoma. PATIENTS AND METHODS: Fifty-one patients, undergoing radical surgery with total mesorectal excision, were examined with reference to regional lymph node status. MRI and pathological findings were compared, and an optimal preoperative criterion was clarified by receiver operating characteristic (ROC) analysis. RESULTS: Among size, shape and internal structure criteria, size was a significant factor for diagnosing metastatic lymph node on MRI. ROC analysis showed that a criterion of 6-mm or larger in the longitudinal axis was the most reliable in differentiating metastatic and non-metastatic lymph nodes, with overall accuracy of 78%. CONCLUSION: A 6-mm longitudinal diameter criterion is thought to be most optimal in the evaluation of mesorectal lymph node status in patients with rectal carcinoma.
BACKGROUND: Preoperative diagnosis of lymph node metastasis is often difficult. A number of different criteria have been advocated in the literature, however, an optimal criterion has not yet been determined in patients with rectal carcinoma. PATIENTS AND METHODS: Fifty-one patients, undergoing radical surgery with total mesorectal excision, were examined with reference to regional lymph node status. MRI and pathological findings were compared, and an optimal preoperative criterion was clarified by receiver operating characteristic (ROC) analysis. RESULTS: Among size, shape and internal structure criteria, size was a significant factor for diagnosing metastatic lymph node on MRI. ROC analysis showed that a criterion of 6-mm or larger in the longitudinal axis was the most reliable in differentiating metastatic and non-metastatic lymph nodes, with overall accuracy of 78%. CONCLUSION: A 6-mm longitudinal diameter criterion is thought to be most optimal in the evaluation of mesorectal lymph node status in patients with rectal carcinoma.
Authors: Joonsung Choi; Soon Nam Oh; Dong-Myung Yeo; Won Kyung Kang; Chan-Kwon Jung; Sang Woo Kim; Michael Yong Park Journal: World J Gastroenterol Date: 2015-01-14 Impact factor: 5.742
Authors: Armin Wiegering; Christoph Isbert; Ulrich A Dietz; Volker Kunzmann; Sabine Ackermann; Alexander Kerscher; Uwe Maeder; Michael Flentje; Nicolas Schlegel; Joachim Reibetanz; Christoph-Thomas Germer; Ingo Klein Journal: BMC Cancer Date: 2014-11-06 Impact factor: 4.430
Authors: Min Ju Kim; Bo Yun Hur; Eun Sun Lee; Boram Park; Jungnam Joo; Min Jung Kim; Sung Chan Park; Ji Yeon Baek; Hee Jin Chang; Dae Yong Kim; Jae Hwan Oh Journal: PLoS One Date: 2018-04-12 Impact factor: 3.240