| Literature DB >> 15734640 |
Abstract
The paradigm for matrix metalloprotease inhibition combines active site tailoring and catalytic zinc ligation. But, selectivity has been difficult. Now, Engel et al. present novel compounds, completely selective for MMP-13, with a unique binding mode.Entities:
Mesh：
Substances：
Year: 2005 PMID： 15734640 DOI： 10.1016/j.chembiol.2005.01.008
Source DB: PubMed Journal: Chem Biol ISSN： 1074-5521