OBJECTIVE: To observe the influence of chemotherapy on the switching of Th1/Th2 cytokines in stomach cancer patients. METHODS: Th1/Th2 cytokine genes expressed by peripheral blood mononuclear cells of stomach cancer patients before and after chemotherapy were detected by RT-PCR. RESULTS: The expression of Th2 cytokines was dominant in patients before chemotherapy, and the dominancy became less marked after chemotherapy. CONCLUSION: The immune deviation with Th2 predominance in stomach cancer patients has a tendency to become reversed after chemotherapy.
OBJECTIVE: To observe the influence of chemotherapy on the switching of Th1/Th2 cytokines in stomach cancerpatients. METHODS:Th1/Th2 cytokine genes expressed by peripheral blood mononuclear cells of stomach cancerpatients before and after chemotherapy were detected by RT-PCR. RESULTS: The expression of Th2 cytokines was dominant in patients before chemotherapy, and the dominancy became less marked after chemotherapy. CONCLUSION: The immune deviation with Th2 predominance in stomach cancerpatients has a tendency to become reversed after chemotherapy.