| Literature DB >> 15733063 |
Abstract
The oocyte is a highly differentiated cell. It makes organelles specialized to its unique functions and progresses through a series of developmental stages to acquire a fertilization competent phenotype. This review will integrate the biology of the oocyte with what is known about oocyte-specific gene regulation and transcription factors involved in oocyte development. We propose that oogenesis is reliant on a dynamic gene regulatory network that includes oocyte-specific transcriptional regulators.Mesh:
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Year: 2005 PMID: 15733063 DOI: 10.1111/j.1432-0436.2005.07301005.x
Source DB: PubMed Journal: Differentiation ISSN: 0301-4681 Impact factor: 3.880