OBJECTIVE: To compare FNAC with histopathology as an alternate method of diagnosing cutaneous leishmaniasis. DESIGN: Comparative study. PLACE AND DURATION OF STUDY: The duration of the study was from August 2003 to April 2004 at CMH, Peshawar. MATERIALS AND METHODS: A total of 40 patients were included in this study. They were referred from various areas of North-West Frontier Province. FNAC and skin biopsy was performed on every patient. Haematoxylin and eosin (H&E) stain was used for both procedures. RESULTS: The study group included 39 males and one female, their age ranging from 8-60 years with a mean age of 31.97 years. Detection of LT bodies was considered as a single criterion of the positive result. Histopathological examination was able to diagnose 14 out of 40 patients (positive yield of 35%), while FNAC picked up 11 out of 40 patients (positive yield of 27.5%). CONCLUSION: FNAC is easier, less painful and more cost-effective than the conventional skin biopsy. The high sensitivity and specificity eliminate the need for other time-consuming and invasive procedures. However, if LT bodies are not detected then any further comment cannot be made regarding the diagnosis and it is necessary to perform skin biopsy.
OBJECTIVE: To compare FNAC with histopathology as an alternate method of diagnosing cutaneous leishmaniasis. DESIGN: Comparative study. PLACE AND DURATION OF STUDY: The duration of the study was from August 2003 to April 2004 at CMH, Peshawar. MATERIALS AND METHODS: A total of 40 patients were included in this study. They were referred from various areas of North-West Frontier Province. FNAC and skin biopsy was performed on every patient. Haematoxylin and eosin (H&E) stain was used for both procedures. RESULTS: The study group included 39 males and one female, their age ranging from 8-60 years with a mean age of 31.97 years. Detection of LT bodies was considered as a single criterion of the positive result. Histopathological examination was able to diagnose 14 out of 40 patients (positive yield of 35%), while FNAC picked up 11 out of 40 patients (positive yield of 27.5%). CONCLUSION: FNAC is easier, less painful and more cost-effective than the conventional skin biopsy. The high sensitivity and specificity eliminate the need for other time-consuming and invasive procedures. However, if LT bodies are not detected then any further comment cannot be made regarding the diagnosis and it is necessary to perform skin biopsy.
Authors: Hafizur Rahman; Mohammad A Razzak; Bikash C Chanda; Khondaker R H Bhaskar; Dinesh Mondal Journal: J Health Popul Nutr Date: 2014-06 Impact factor: 2.000