Literature DB >> 15730504

Histoplasmine and paracoccidiodine epidemiological study in Upata, Bolívar state, Venezuela.

Julman R Cermeño1, Julmery J Cermeño, Isabel Hernández, Gerardo Godoy, July J Cermeño, Ismery Cabello, Yida Orellán, Ytalia Blanco, Salvador Penna.   

Abstract

OBJECTIVE: To determine the prevalence of histoplasmosis and paracoccidiomycosis in Upata, a city in Bolivar state, Venezuela.
METHODS: Cutaneous tests on 397 volunteers, 204 with histoplasmine and 193 with paracoccidioidine. Epidemiological data were collected in a protocol sheet. Readings were performed at 24 and 48 h post-injection, by the same observer, and a positive reaction was defined as hardened papule of 5 mm or more.
RESULTS: Histoplasmine tests were positive in 19.6% and 34.0% at 24 and 48 h after antigens injection with a significant increase of reactivity (P=0.0019). Paracoccidiodine tests were positive in 11.3% and 19.7% at 24 and 48 h respectively and this difference was also significant (P=0.004). Risk factors which could explain these levels of reactivity could not be clearly identified. Cultures and animal inoculation from soil samples for fungus isolation were negative.
CONCLUSIONS: Paracoccidioidomycoses and histoplasmosis are endemic in Upata.

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Year:  2005        PMID: 15730504     DOI: 10.1111/j.1365-3156.2004.01376.x

Source DB:  PubMed          Journal:  Trop Med Int Health        ISSN: 1360-2276            Impact factor:   2.622


  8 in total

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  8 in total

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