Literature DB >> 1573033

A group of potassium-channel blockers-acetylcholine releasers: new potentials for Alzheimer disease? A review.

E P Lavretsky1, L F Jarvik.   

Abstract

This review of the literature examines systematically the data currently available for potassium-channel blockers to reassess their clinical potential in Alzheimer disease. The conclusion is that potassium-channel blockers may have been dismissed prematurely for the treatment of Alzheimer disease, an impression supported by data indicating intimate relationships between potassium-channel blockade and cholinergic transmission.

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Year:  1992        PMID： 1573033

Source DB:  PubMed          Journal:  J Clin Psychopharmacol        ISSN： 0271-0749            Impact factor:   3.153


  6 in total

Review 1.  Repositioning medication for cardiovascular and cerebrovascular disease to delay the onset and prevent progression of Alzheimer's disease.

Authors:  Heeyoung Lee; EunYoung Kim
Journal:  Arch Pharm Res       Date:  2020-09-09       Impact factor: 4.946

2.  Lack of effect of Z-butylidenephthalide on presynaptic N-type Ca²⁺ channels in isolated guinea-pig ileum.

Authors:  Marcelo Chen; Wun-Chang Ko
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2016-02       Impact factor: 3.000

Review 3.  Neuropathobiology of senile dementia and mechanism of action of nootropic drugs.

Authors:  O Benesová
Journal:  Drugs Aging       Date:  1994-04       Impact factor: 3.923

4.  Butylidenephthalide antagonizes cromakalim-induced systolic pressure reduction in conscious normotensive rats.

Authors:  Chung-Hung Shih; Yu-Jing Lin; Chi-Ming Chen; Wun-Chang Ko
Journal:  BMC Complement Altern Med       Date:  2015-10-05       Impact factor: 3.659

5.  Butylidenephthalide blocks potassium channels and enhances basal tension in isolated guinea-pig trachea.

Authors:  Hsin-Te Hsu; You-Lan Yang; Wan-Chen Chen; Chi-Ming Chen; Wun-Chang Ko
Journal:  Biomed Res Int       Date:  2014-07-10       Impact factor: 3.411

6.  Short-Term High-Fat Diet (HFD) Induced Anxiety-Like Behaviors and Cognitive Impairment Are Improved with Treatment by Glyburide.

Authors:  Stephen J Gainey; Kristin A Kwakwa; Julie K Bray; Melissa M Pillote; Vincent L Tir; Albert E Towers; Gregory G Freund
Journal:  Front Behav Neurosci       Date:  2016-08-11       Impact factor: 3.558
  6 in total

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