PURPOSE: To evaluate the diagnostic accuracy of 16-row multislice spiral computed tomography coronary angiography (16-MSCT-CA) for the non-invasive assessment of significant coronary artery stenosis. MATERIALS AND METHODS: We enrolled 40 patients (36 male, aged 59+/-11 yrs) with suspected obstructive coronary artery disease and a heart rate <65 bpm during the scan. The 16-MSCT-CA (Sensation 16, Siemens, Forchheim, Germany) was performed with electrocardiographically-gated technique after the intravenous administration of 100 ml of iodinated contrast material followed by a saline bolus chaser. The scan parameters were: collimation 16 x 0.75 mm, rotation time 0.42 s, feed/rot. 3 mm (pitch 0.25), 120 kVp, 500 mAs. All coronary segments = or >2 mm in diameter were evaluated by two independent observers for the presence of significant coronary artery stenosis (= or >50%). Consensus reading was compared to quantitative coronary angiography. RESULTS: The average heart rate was 55+/-6 bpm. Of the 428 segments of = or >2.0 mm diameter 92 were significantly diseased. Without exclusion of any branches (428), the sensitivity, specificity, positive, and negative predictive values to identify = or >50% obstructed segments were 95.7% (88/92), 95.8% (322/336), 86.3% (88/102), and 98.8% (322/326), respectively. No occluded left main, left anterior descending, circumflex or right coronary artery segments remained undetected. CONCLUSIONS: 16-MSCT-CA in a selected low-heart-rate patient population provides high diagnostic accuracy in the evaluation of significant coronary artery stenosis.
PURPOSE: To evaluate the diagnostic accuracy of 16-row multislice spiral computed tomography coronary angiography (16-MSCT-CA) for the non-invasive assessment of significant coronary artery stenosis. MATERIALS AND METHODS: We enrolled 40 patients (36 male, aged 59+/-11 yrs) with suspected obstructive coronary artery disease and a heart rate <65 bpm during the scan. The 16-MSCT-CA (Sensation 16, Siemens, Forchheim, Germany) was performed with electrocardiographically-gated technique after the intravenous administration of 100 ml of iodinated contrast material followed by a saline bolus chaser. The scan parameters were: collimation 16 x 0.75 mm, rotation time 0.42 s, feed/rot. 3 mm (pitch 0.25), 120 kVp, 500 mAs. All coronary segments = or >2 mm in diameter were evaluated by two independent observers for the presence of significant coronary artery stenosis (= or >50%). Consensus reading was compared to quantitative coronary angiography. RESULTS: The average heart rate was 55+/-6 bpm. Of the 428 segments of = or >2.0 mm diameter 92 were significantly diseased. Without exclusion of any branches (428), the sensitivity, specificity, positive, and negative predictive values to identify = or >50% obstructed segments were 95.7% (88/92), 95.8% (322/336), 86.3% (88/102), and 98.8% (322/326), respectively. No occluded left main, left anterior descending, circumflex or right coronary artery segments remained undetected. CONCLUSIONS: 16-MSCT-CA in a selected low-heart-rate patient population provides high diagnostic accuracy in the evaluation of significant coronary artery stenosis.
Authors: F Cademartiri; R Malagò; M Belgrano; F Alberghina; E Maffei; L La Grutta; A A Palumbo; G Runza; N R Mollet; M Midiri; G P Krestin; R Pozzi Mucelli Journal: Radiol Med Date: 2007-10-21 Impact factor: 3.469
Authors: F Cademartiri; L La Grutta; A Palumbo; E Maffei; A Aldrovandi; R Malagò; F Alberghina; F Pugliese; G Runza; M Belgrano; M Midiri; M A Cova; G P Krestin Journal: Radiol Med Date: 2007-07-24 Impact factor: 3.469
Authors: E Maffei; C Martini; C Tedeschi; P Spagnolo; A Zuccarelli; T Arcadi; A Guaricci; S Seitun; A Weustink; N Mollet; F Cademartiri Journal: Radiol Med Date: 2011-06-04 Impact factor: 3.469
Authors: E Maffei; C Martini; C Tedeschi; P Spagnolo; A Zuccarelli; T Arcadi; A Guaricci; S Seitun; A C Weustink; N R Mollet; F Cademartiri Journal: Radiol Med Date: 2011-06-04 Impact factor: 3.469
Authors: R Malagò; A Pezzato; C Barbiani; W Mantovani; G Caliari; U Alfonsi; D Tavella; R Pozzi Mucelli Journal: Radiol Med Date: 2011-09-02 Impact factor: 3.469
Authors: Benjamin J W Chow; Carole Dennie; Udo Hoffmann; Derek So; Robert A de Kemp; Terrence D Ruddy; Rob S Beanlands Journal: Can J Cardiol Date: 2007-08 Impact factor: 5.223