Preliminary experience with cultured epidermal autograft in a community hospital burn unit.

Initial experience with cultured epidermal autograft (CEA) in a community hospital burn unit is described. Five applications of CEA to three patients (mean burn size, 59% total body surface area) were made. Final graft "take" of CEA ranged from 10% to 80%. Healed CEA is cosmetically superior to meshed autograft and appears to form less hypertrophic scar tissue. CEA is more sensitive to infection than meshed autograft. A review of the literature concerning topical antibiotic use with CEA is included. This experience with CEA demonstrates that large burns can be successfully managed with this modality in a community hospital burn unit setting.