| Literature DB >> 15727879 |
Søren Ebdrup1, Poul Jacobsen, Anupma Dhanda Farrington, Per Vedsø.
Abstract
A range of aryl and heteroaryl boronic acids were tested for their in vitro hormone-sensitive lipase inhibitory properties. (2-Benzyloxy-5-fluorophenyl)boronic acid, (2-benzyloxy-5-chlorophenyl)boronic acid and 5-bromothiophene-2-boronic acid were found to be the most potent HSL inhibitors with IC(50) values of 140, 17 and 350 nM, respectively.Entities:
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Year: 2005 PMID： 15727879 DOI： 10.1016/j.bmc.2004.12.042
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641