Literature DB >> 15726996

Patenting humans: clones, chimeras, and biological artifacts.

William B Hurlbut1.   

Abstract

The momentum of advances in biology is evident in the history of patents on life forms. As we proceed forward with greater understanding and technological control of developmental biology there will be many new and challenging dilemmas related to patenting of human parts and partial trajectories of human development. These dilemmas are already evident in the current conflict over the moral status of the early human embryo. In this essay, recent evidence from embryological studies is considered and the unbroken continuity of organismal development initiated at fertilization is asserted as clear and reasonable grounds for moral standing. Within this frame of analysis, it is proposed that through a technique of Altered Nuclear Transfer, non-organismal entities might be created from which embryonic stem cells could be morally procured. Criteria for patenting of such non-organismal entities are considered.

Entities:  

Keywords:  Biomedical and Behavioral Research; Genetics and Reproduction

Mesh:

Year:  2005        PMID: 15726996     DOI: 10.1007/s11948-005-0052-x

Source DB:  PubMed          Journal:  Sci Eng Ethics        ISSN: 1353-3452            Impact factor:   3.525


  5 in total

1.  Your destiny, from day one.

Authors:  Helen Pearson
Journal:  Nature       Date:  2002-07-04       Impact factor: 49.962

2.  Monozygotic twins and transfer at the blastocyst stage after ICSI.

Authors:  A L da Costa AL; S Abdelmassih; F G de Oliveira ; V Abdelmassih; R Abdelmassih; Z P Nagy; J P Balmaceda
Journal:  Hum Reprod       Date:  2001-02       Impact factor: 6.918

3.  Role for sperm in spatial patterning of the early mouse embryo.

Authors:  K Piotrowska; M Zernicka-Goetz
Journal:  Nature       Date:  2001-01-25       Impact factor: 49.962

Review 4.  Using EC and ES cell culture to study early development: recent observations on Indian hedgehog and Bmps.

Authors:  L Grabel; S Becker; L Lock; P Maye; T Zanders
Journal:  Int J Dev Biol       Date:  1998       Impact factor: 2.203

5.  Specification of embryonic axes begins before cleavage in normal mouse development.

Authors:  R L Gardner
Journal:  Development       Date:  2001-03       Impact factor: 6.868

  5 in total
  3 in total

1.  Observations on a meeting on the ethics of intellectual property rights and patents.

Authors:  Raymond Spier
Journal:  Sci Eng Ethics       Date:  2005-01       Impact factor: 3.525

Review 2.  Potentiality of embryonic stem cells: an ethical problem even with alternative stem cell sources.

Authors:  H-W Denker
Journal:  J Med Ethics       Date:  2006-11       Impact factor: 2.903

Review 3.  Wishful thinking will not obviate embryo use.

Authors:  Louis M Guenin
Journal:  Stem Cell Rev       Date:  2005-12       Impact factor: 5.739

  3 in total

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