Literature DB >> 15724986

Peptide-cleaving catalyst selective for peptide deformylase.

Pil Seok Chae1, Myoung-Soon Kim, Chul-Seung Jeung, Seong Du Lee, Hwangseo Park, Sangyoub Lee, Junghun Suh.   

Abstract

A peptide-cleaving catalyst selective for peptide deformylase (PDF) was obtained from a library containing about 15 000 catalyst candidates. The catalyst cleaved the polypeptide backbone of PDF at Gln(152)-Arg(153). Docking simulations suggested multiple modes of interactions in the complex formed between the catalyst and PDF.

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Year:  2005        PMID： 15724986     DOI： 10.1021/ja044043h

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  10 in total

1.  Cleavage agents for soluble oligomers of human islet amyloid polypeptide.

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Review 2.  Application of metal coordination chemistry to explore and manipulate cell biology.

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3.  Peptide-cleaving catalyst selective for melanin-concentrating hormone: Oxidative decarboxylation of N-terminal aspartate catalyzed by Co(III)cyclen.

Authors:  Min Gyum Kim; Myoung-soon Kim; Seong Du Lee; Junghun Suh
Journal:  J Biol Inorg Chem       Date:  2006-07-13       Impact factor: 3.358

4.  Angiotensin-cleaving catalysts: conversion of N-terminal aspartate to pyruvate through oxidative decarboxylation catalyzed by Co(III)cyclen.

Authors:  Myoung-Soon Kim; Joong Won Jeon; Junghun Suh
Journal:  J Biol Inorg Chem       Date:  2005-05-11       Impact factor: 3.358

5.  New chelating ligands for Co(III)-based peptide-cleaving catalysts selective for pathogenic proteins of amyloidoses.

Authors:  Woo Suk Chei; Heeyeon Ju; Junghun Suh
Journal:  J Biol Inorg Chem       Date:  2010-12-18       Impact factor: 3.358

6.  Self-subunit swapping chaperone needed for the maturation of multimeric metalloenzyme nitrile hydratase by a subunit exchange mechanism also carries out the oxidation of the metal ligand cysteine residues and insertion of cobalt.

Authors:  Zhemin Zhou; Yoshiteru Hashimoto; Michihiko Kobayashi
Journal:  J Biol Chem       Date:  2009-04-03       Impact factor: 5.157

7.  Proteolytic activity of Co(III) complex of 1-oxa-4,7,10-triazacyclododecane: a new catalytic center for peptide-cleavage agents.

Authors:  Hye Mi Kim; Boonjae Jang; Young Eun Cheon; Myunghyun Paik Suh; Junghun Suh
Journal:  J Biol Inorg Chem       Date:  2008-10-05       Impact factor: 3.358

8.  Metallotherapeutics: novel strategies in drug design.

Authors:  Lalintip Hocharoen; James A Cowan
Journal:  Chemistry       Date:  2009-09-07       Impact factor: 5.236

Review 9.  Amide Bond Activation of Biological Molecules.

Authors:  Sriram Mahesh; Kuei-Chien Tang; Monika Raj
Journal:  Molecules       Date:  2018-10-12       Impact factor: 4.411

10.  Self-subunit swapping occurs in another gene type of cobalt nitrile hydratase.

Authors:  Yi Liu; Wenjing Cui; Yuanyuan Xia; Youtian Cui; Michihiko Kobayashi; Zhemin Zhou
Journal:  PLoS One       Date:  2012-11-30       Impact factor: 3.240
  10 in total

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