BACKGROUND: Since little is known about the long-term course and outcome of bulimia nervosa, the authors designed a 12-year prospective longitudinal study with five cross-sectional assessments based on a large sample of consecutively treated females with bulimia nervosa (purging type) (BN-P). METHOD: One hundred and ninety-six females with BN-P were assessed (1) at the beginning of treatment, (2) at the end of treatment, (3) at 2-year follow-up, (4) at 6-year follow-up, and (5) at 12-year follow-up. In self-ratings as well as expert ratings based on interviews we assessed specific eating-disorder and general psychopathology. RESULTS: The general pattern of results over time showed substantial improvement during treatment, slight (in most cases non-significant) decline during the first two years after the end of treatment, and further improvement and stabilization until 12-year follow-up. At that point the majority of patients (70.1 %) showed no major DSM-IV eating disorder, 13.2% had eating disorders not otherwise specified, 10.1 % had BN-P and 2% had died. Very few had undergone transition to anorexia nervosa or binge-eating disorders. Logistic regression analyses showed that psychiatric co-morbidity was the best and most stable predictor for eating-disorder outcome at 2, 6 and 12 years. CONCLUSIONS: Course and outcome of BN-P was generally more favourable than for anorexia nervosa.
BACKGROUND: Since little is known about the long-term course and outcome of bulimia nervosa, the authors designed a 12-year prospective longitudinal study with five cross-sectional assessments based on a large sample of consecutively treated females with bulimia nervosa (purging type) (BN-P). METHOD: One hundred and ninety-six females with BN-P were assessed (1) at the beginning of treatment, (2) at the end of treatment, (3) at 2-year follow-up, (4) at 6-year follow-up, and (5) at 12-year follow-up. In self-ratings as well as expert ratings based on interviews we assessed specific eating-disorder and general psychopathology. RESULTS: The general pattern of results over time showed substantial improvement during treatment, slight (in most cases non-significant) decline during the first two years after the end of treatment, and further improvement and stabilization until 12-year follow-up. At that point the majority of patients (70.1 %) showed no major DSM-IV eating disorder, 13.2% had eating disorders not otherwise specified, 10.1 % had BN-P and 2% had died. Very few had undergone transition to anorexia nervosa or binge-eating disorders. Logistic regression analyses showed that psychiatric co-morbidity was the best and most stable predictor for eating-disorder outcome at 2, 6 and 12 years. CONCLUSIONS: Course and outcome of BN-P was generally more favourable than for anorexia nervosa.
Authors: Leslie K Anderson; Erin E Reilly; Laura Berner; Christina E Wierenga; Michelle D Jones; Tiffany A Brown; Walter H Kaye; Anne Cusack Journal: Curr Psychiatry Rep Date: 2017-08 Impact factor: 5.285
Authors: Kamryn T Eddy; Nassim Tabri; Jennifer J Thomas; Helen B Murray; Aparna Keshaviah; Elizabeth Hastings; Katherine Edkins; Meera Krishna; David B Herzog; Pamela K Keel; Debra L Franko Journal: J Clin Psychiatry Date: 2017-02 Impact factor: 4.384
Authors: Matislava Karačić; Jackie A Wales; Jon Arcelus; Robert L Palmer; Zafra Cooper; Christopher G Fairburn Journal: Behav Res Ther Date: 2011-06-13