Literature DB >> 15724207

Evidence for a hydrogen abstraction mechanism in P450-catalyzed N-dealkylations.

Mehul Bhakta1, Paul F Hollenberg, Kandatege Wimalasena.   

Abstract

The experimental evidence presented in this manuscript suggest against the widely accepted single electron/proton transfer mechanism for P450 catalyzed N-dealkylations and provides strong support for a hydrogen atom abstraction mechanism.

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Year:  2004        PMID： 15724207     DOI： 10.1039/b412221f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

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Journal:  Inorg Chem       Date:  2008-09-11       Impact factor: 5.165
  4 in total

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