Literature DB >> 15723787

TOR signaling: an odyssey from cellular stress to the cell growth machinery.

Robert T Abraham1.   

Abstract

The target of rapamycin (TOR) protein kinase is centrally involved in the coordination of cell growth and proliferation with the availability of growth factors and nutrients. Two recent reports have illuminated a mechanism whereby hypoxic stress dampens TOR signaling in metazoan cells.

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Year:  2005        PMID： 15723787     DOI： 10.1016/j.cub.2005.02.015

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  10 in total

1.  Arabidopsis TARGET OF RAPAMYCIN interacts with RAPTOR, which regulates the activity of S6 kinase in response to osmotic stress signals.

Authors:  Magdy M Mahfouz; Sunghan Kim; Ashton J Delauney; Desh Pal S Verma
Journal:  Plant Cell       Date:  2005-12-23       Impact factor: 11.277

2.  Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease.

Authors:  Min Peng; Julian Ostrovsky; Young Joon Kwon; Erzsebet Polyak; Joseph Licata; Mai Tsukikawa; Eric Marty; Jeffrey Thomas; Carolyn A Felix; Rui Xiao; Zhe Zhang; David L Gasser; Yair Argon; Marni J Falk
Journal:  Hum Mol Genet       Date:  2015-06-03       Impact factor: 6.150

3.  Hypoxia-induced energy stress inhibits the mTOR pathway by activating an AMPK/REDD1 signaling axis in head and neck squamous cell carcinoma.

Authors:  Abraham Schneider; Rania H Younis; J Silvio Gutkind
Journal:  Neoplasia       Date:  2008-11       Impact factor: 5.715

Review 4.  Involvement of redox state in the aging of Drosophila melanogaster.

Authors:  William C Orr; Svetlana N Radyuk; Rajindar S Sohal
Journal:  Antioxid Redox Signal       Date:  2013-04-06       Impact factor: 8.401

5.  A retroinhibition approach reveals a tumor cell-autonomous response to rapamycin in head and neck cancer.

Authors:  Panomwat Amornphimoltham; Vyomesh Patel; Kantima Leelahavanichkul; Robert T Abraham; J Silvio Gutkind
Journal:  Cancer Res       Date:  2008-02-15       Impact factor: 12.701

6.  Chronic hypoxia impairs muscle function in the Drosophila model of Duchenne's muscular dystrophy (DMD).

Authors:  Matias Mosqueira; Gabriel Willmann; Hannele Ruohola-Baker; Tejvir S Khurana
Journal:  PLoS One       Date:  2010-10-20       Impact factor: 3.240

7.  Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling.

Authors:  Atul S Deshmukh; Jonas T Treebak; Yun Chau Long; Benoit Viollet; Jørgen F P Wojtaszewski; Juleen R Zierath
Journal:  Mol Endocrinol       Date:  2008-02-14

8.  Insights into the domain and repeat architecture of target of rapamycin.

Authors:  Bruce A Knutson
Journal:  J Struct Biol       Date:  2010-01-11       Impact factor: 2.867

9.  Pioneer Factors FOXA1 and FOXA2 Assist Selective Glucocorticoid Receptor Signaling in Human Endometrial Cells.

Authors:  Shannon Whirledge; Edwina P Kisanga; Robert N Taylor; John A Cidlowski
Journal:  Endocrinology       Date:  2017-11-01       Impact factor: 4.736

10.  DDIT4/REDD1/RTP801 is a novel negative regulator of Schwann cell myelination.

Authors:  Roberta Noseda; Sophie Belin; Françoise Piguet; Ilaria Vaccari; Stefania Scarlino; Paola Brambilla; Filippo Martinelli Boneschi; Maria Laura Feltri; Lawrence Wrabetz; Angelo Quattrini; Elena Feinstein; Richard L Huganir; Alessandra Bolino
Journal:  J Neurosci       Date:  2013-09-18       Impact factor: 6.167
  10 in total

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