PURPOSE: To estimate the prevalence of metabolic syndrome in persons with a history of cancer from a population-based sample of adults, and compare that prevalence to persons without a history of cancer. METHODS: Data from the Third National Health and Nutrition Examination Survey were analyzed to compare prevalence and prevalence differences of the metabolic syndrome, as defined by Adult Treatment Panel III criteria, between 486 persons with a reported history of cancer and 12,526 persons with no reported history of cancer. RESULTS: The prevalence of metabolic syndrome was 258/1000 persons for those with a cancer history and 184/1000 persons among those without, resulting in a prevalence difference of 74/1000 persons (95% CI, 38-110). Prevalence differences varied substantially by age at interview. The prevalence difference was highest among those aged 40 to 49 years (112/1000 persons) and 50 to 59 years (73/1000 persons), while those in younger (18-39 years) and older (: 60 years) age groups had a moderately higher prevalence among those without a cancer history. CONCLUSION: These results add to the emerging concern that metabolic syndrome and associated risks for cardiovascular disease and type 2 diabetes may be an adverse late effect of cancer and/or its treatment.
PURPOSE: To estimate the prevalence of metabolic syndrome in persons with a history of cancer from a population-based sample of adults, and compare that prevalence to persons without a history of cancer. METHODS: Data from the Third National Health and Nutrition Examination Survey were analyzed to compare prevalence and prevalence differences of the metabolic syndrome, as defined by Adult Treatment Panel III criteria, between 486 persons with a reported history of cancer and 12,526 persons with no reported history of cancer. RESULTS: The prevalence of metabolic syndrome was 258/1000 persons for those with a cancer history and 184/1000 persons among those without, resulting in a prevalence difference of 74/1000 persons (95% CI, 38-110). Prevalence differences varied substantially by age at interview. The prevalence difference was highest among those aged 40 to 49 years (112/1000 persons) and 50 to 59 years (73/1000 persons), while those in younger (18-39 years) and older (: 60 years) age groups had a moderately higher prevalence among those without a cancer history. CONCLUSION: These results add to the emerging concern that metabolic syndrome and associated risks for cardiovascular disease and type 2 diabetes may be an adverse late effect of cancer and/or its treatment.
Authors: Kyae Hyung Kim; Young Youn Cho; Dong Wook Shin; Ju Hyun Lee; Young-Jin Ko; Sang Min Park Journal: Support Care Cancer Date: 2013-08-18 Impact factor: 3.603
Authors: Kris Ann P Schultz; Lu Chen; Zhengjia Chen; Lonnie K Zeltzer; H Stacy Nicholson; Joseph P Neglia Journal: Pediatr Blood Cancer Date: 2010-07-15 Impact factor: 3.167
Authors: Lillian R Meacham; Eric J Chow; Kirsten K Ness; Kala Y Kamdar; Yan Chen; Yutaka Yasui; Kevin C Oeffinger; Charles A Sklar; Leslie L Robison; Ann C Mertens Journal: Cancer Epidemiol Biomarkers Prev Date: 2010-01 Impact factor: 4.254
Authors: N S Majhail; M E Flowers; K K Ness; M Jagasia; P A Carpenter; M Arora; S Arai; L Johnston; P J Martin; K S Baker; S J Lee; L J Burns Journal: Bone Marrow Transplant Date: 2008-08-25 Impact factor: 5.483