Literature DB >> 15722257

Epstein-Barr virus etiology in rheumatoid synovitis.

Shigemasa Sawada1, Masami Takei.   

Abstract

The etiology of rheumatoid arthritis (RA) has remained unknown, although it has been investigated and speculated that both genetic and environmental components contribute to the cause of this disease. Epstein-Barr virus (EBV) has been a strong candidate about for over 25 years as environmental infectious agent(s). There are many circumstantial evidence for association between EBV and RA, but definite evidence is wanting. In present article, we review an increase circumstantial proof which has been investigated so far and demonstrate direct evidence for the presence of EBV in inflamed synovial cells in patients with RA and discuss on the recent finding of signaling lymphocytic-activation molecule (SLAM)-associated protein (SAP), which opened a new approach to understand on impaired function of cytotoxic T cell for EBV in patients with RA.

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Year:  2005        PMID： 15722257     DOI： 10.1016/j.autrev.2004.08.034

Source DB:  PubMed          Journal:  Autoimmun Rev        ISSN： 1568-9972            Impact factor:   9.754


  8 in total

1.  A role for human endogenous retrovirus-K (HML-2) in rheumatoid arthritis: investigating mechanisms of pathogenesis.

Authors:  G Freimanis; P Hooley; H Davari Ejtehadi; H A Ali; A Veitch; P B Rylance; A Alawi; J Axford; A Nevill; P G Murray; P N Nelson
Journal:  Clin Exp Immunol       Date:  2010-03-16       Impact factor: 4.330

Review 2.  SLAMF6 in health and disease: Implications for therapeutic targeting.

Authors:  Burcu Yigit; Ninghai Wang; Roland W Herzog; Cox Terhorst
Journal:  Clin Immunol       Date:  2018-10-23       Impact factor: 3.969

Review 3.  Rheumatoid arthritis is linked to Proteus--the evidence.

Authors:  Taha Rashid; Alan Ebringer
Journal:  Clin Rheumatol       Date:  2007-01-06       Impact factor: 3.650

4.  The clinical impact of absolute lymphocyte count in peripheral blood among patients with methotrexate - associated lymphoproliferative disorders.

Authors:  Michihide Tokuhira; Yuka Tanaka; Yasuyuki Takahashi; Yuta Kimura; Tatsuki Tomikawa; Tomoe Anan; Junichi Watanabe; Morihiko Sagawa; Morihiro Higashi; Shuju Momose; Koichi Amano; Takayuki Tabayashi; Reiko Nakaseko; Jun-Ichi Tamaru; Masahiro Kizaki
Journal:  J Clin Exp Hematop       Date:  2020-05-13

Review 5.  Are Viral Infections Key Inducers of Autoimmune Diseases? Focus on Epstein-Barr Virus.

Authors:  Masami Takei; Noboru Kitamura; Yosuke Nagasawa; Hiroshi Tsuzuki; Mitsuhiro Iwata; Yasuko Nagatsuka; Hideki Nakamura; Kenichi Imai; Shigeyoshi Fujiwara
Journal:  Viruses       Date:  2022-08-27       Impact factor: 5.818

Review 6.  Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy.

Authors:  Dinesh Adhikary; Uta Behrends; Heike Boerschmann; Andrea Pfünder; Stefan Burdach; Andreas Moosmann; Klaus Witter; Georg W Bornkamm; Josef Mautner
Journal:  PLoS One       Date:  2007-07-04       Impact factor: 3.240

7.  Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain.

Authors:  Barbara Serafini; Barbara Rosicarelli; Diego Franciotta; Roberta Magliozzi; Richard Reynolds; Paola Cinque; Laura Andreoni; Pankaj Trivedi; Marco Salvetti; Alberto Faggioni; Francesca Aloisi
Journal:  J Exp Med       Date:  2007-11-05       Impact factor: 14.307

Review 8.  High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?

Authors:  Ranjeny Thomas; Malcolm Turner; Andrew P Cope
Journal:  Arthritis Res Ther       Date:  2008-07-24       Impact factor: 5.156
  8 in total

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