| Literature DB >> 15722221 |
Claire Delahunty1, John R Yates.
Abstract
Multidimensional liquid chromatography techniques have been coupled to tandem mass spectrometry to provide a robust method to identify proteins in complex mixtures. Data acquisition is interfaced directly with search algorithms for identification through cross-correlation with databases. This review describes the most recent advances in methodologies for protein identification by mass spectrometry and describes the limitations of the application of the technologies.Mesh:
Substances:
Year: 2005 PMID: 15722221 DOI: 10.1016/j.ymeth.2004.08.016
Source DB: PubMed Journal: Methods ISSN: 1046-2023 Impact factor: 3.608