Literature DB >> 15719629

[Progress in research on triptolide].

Ming-xing Liu1, Jing Dong, Ya-jiang Yang, Xiang-liang Yang, Hui-bi Xu.   

Abstract

To further understand triptolide, this paper has introduced the pharmacology, pharmacokinetics, toxicity, the clinic application and semi-synthesis of triptolide on basis of importance and significant contents of reference which have been consulted in the past twenty years. Presently triptolide and Tripterygium wilfordii have been a hot spot of modernization of Chinese traditional medicine. It is very important to develop a new dosage form of high effect and low toxicity by making use of advanced technology according to its characteristics.

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Year:  2005        PMID: 15719629

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  9 in total

Review 1.  Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae).

Authors:  Anita M Brinker; Jun Ma; Peter E Lipsky; Ilya Raskin
Journal:  Phytochemistry       Date:  2007-01-23       Impact factor: 4.072

2.  Triptolide as an Alternative to IVIG Therapy for Kawasaki Disease in a Mouse Model.

Authors:  Zong-Ting Yan; Jian-Wen Zou
Journal:  Balkan Med J       Date:  2013-06-01       Impact factor: 2.021

3.  (5R)-5-Hydroxytriptolide (LLDT-8) inhibits osteoclastogenesis via RANKL/RANK/OPG signaling pathway.

Authors:  Yi Shen; Ting Jiang; Rongsheng Wang; Shijun He; Mengru Guo; Jianping Zuo; Dongyi He
Journal:  BMC Complement Altern Med       Date:  2015-03-24       Impact factor: 3.659

4.  The Protective Effects of Isoliquiritigenin and Glycyrrhetinic Acid against Triptolide-Induced Oxidative Stress in HepG2 Cells Involve Nrf2 Activation.

Authors:  Ling-Juan Cao; Huan-De Li; Miao Yan; Zhi-Hua Li; Hui Gong; Pei Jiang; Yang Deng; Ping-Fei Fang; Bi-Kui Zhang
Journal:  Evid Based Complement Alternat Med       Date:  2016-01-21       Impact factor: 2.629

5.  Therapeutic effects of triptolide via the inhibition of IL-1β expression in a mouse model of ulcerative colitis.

Authors:  Haifeng Zhang; Chen Gong; Lishuai Qu; Xiaoling Ding; Wei Cao; Haiqin Chen; Bin Zhang; Guoxiong Zhou
Journal:  Exp Ther Med       Date:  2016-06-30       Impact factor: 2.447

6.  Protective Effect of 18β-Glycyrrhetinic Acid against Triptolide-Induced Hepatotoxicity in Rats.

Authors:  Guanghua Yang; Lan Wang; Xiuting Yu; Yanfeng Huang; Chang Qu; Zhenbiao Zhang; Dandan Luo; Ji Lin; Lian Zhou; Ziren Su; Xiaojun Zhang; Haiming Chen
Journal:  Evid Based Complement Alternat Med       Date:  2017-05-09       Impact factor: 2.629

7.  Extrahepatic cytochrome P450s play an insignificant role in triptolide-induced toxicity.

Authors:  Yuan Wei; Dujun Wang; Meng Chen; Zhen Ouyang; Shuo Wang; Jun Gu
Journal:  Chin Med       Date:  2018-04-23       Impact factor: 5.455

Review 8.  [Advances on effects of triptolide with non-small cell lung cancer].

Authors:  Li Wang; Yong Song
Journal:  Zhongguo Fei Ai Za Zhi       Date:  2013-07

9.  Cardiac toxicity of Triptergium wilfordii Hook F. may correlate with its inhibition to hERG channel.

Authors:  Wei Zhao; Liping Xiao; Lanying Pan; Xianfu Ke; Yanting Zhang; Dian Zhong; Jianwei Xu; Fumin Cao; Liren Wu; Yuan Chen
Journal:  Heliyon       Date:  2019-10-09
  9 in total

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