Literature DB >> 15719108

Room temperature palladium catalysed coupling of acyl chlorides with terminal alkynes.

Russell J Cox1, Dougal J Ritson, Thomas A Dane, John Berge, Jonathan P H Charmant, Anob Kantacha.   

Abstract

Conditions are reported for the facile, high-yielding coupling of acyl chlorides with terminal alkynes in a reaction involving palladium and copper iodide; the reaction is tolerant of a wide variety of acyl chlorides and terminal alkynes and provides a convenient one-pot route to acetylenic ketones.

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Year:  2005        PMID: 15719108     DOI: 10.1039/b414826f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.

Authors:  Ute F Röhrig; Somi Reddy Majjigapu; Pierre Vogel; Aline Reynaud; Florence Pojer; Nahzli Dilek; Patrick Reichenbach; Kelly Ascenção; Melita Irving; George Coukos; Olivier Michielin; Vincent Zoete
Journal:  J Enzyme Inhib Med Chem       Date:  2022-12       Impact factor: 5.756

2.  Heterocyclic analogs of thioflavones: synthesis and NMR spectroscopic investigations.

Authors:  Ferdinand C Fuchs; Gernot A Eller; Wolfgang Holzer
Journal:  Molecules       Date:  2009-09-25       Impact factor: 4.411

  2 in total

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