Literature DB >> 15719025

The role of BH3-only proteins in the immune system.

Andreas Strasser1.   

Abstract

Programmed cell death--also known as apoptosis--has a crucial role in the immune system of mammals and other animals. It removes useless cells and potentially dangerous cells, including lymphocytes, and is involved in killing pathogen-infected or damaged cells. Defects in this process have been found to cause or contribute to diseases of the immune system, including immunodeficiency, autoimmunity, lymphoma and leukaemia. This review describes BH3-only proteins, a pro-apoptotic subgroup of the BCL-2 family, and their role in the development and function of the immune system.

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Year:  2005        PMID: 15719025     DOI: 10.1038/nri1568

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN: 1474-1733            Impact factor:   53.106


  229 in total

1.  Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis.

Authors:  Pavan Brahmamdam; Shigeaki Inoue; Jacqueline Unsinger; Katherine C Chang; Jonathan E McDunn; Richard S Hotchkiss
Journal:  J Leukoc Biol       Date:  2010-05-18       Impact factor: 4.962

2.  BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs.

Authors:  Emma M Carrington; Ingela B Vikstrom; Amanda Light; Robyn M Sutherland; Sarah L Londrigan; Kylie D Mason; David C S Huang; Andrew M Lew; David M Tarlinton
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-01       Impact factor: 11.205

3.  BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.

Authors:  Miriam Erlacher; Ewa M Michalak; Priscilla N Kelly; Verena Labi; Harald Niederegger; Leigh Coultas; Jerry M Adams; Andreas Strasser; Andreas Villunger
Journal:  Blood       Date:  2005-08-23       Impact factor: 22.113

4.  Increased stability of Bcl-2 in HSP70-mediated protection against apoptosis induced by oxidative stress.

Authors:  Bimei Jiang; Pengfei Liang; Gonghua Deng; Zizhi Tu; Meidong Liu; Xianzhong Xiao
Journal:  Cell Stress Chaperones       Date:  2010-10-03       Impact factor: 3.667

Review 5.  The many roles of FAS receptor signaling in the immune system.

Authors:  Andreas Strasser; Philipp J Jost; Shigekazu Nagata
Journal:  Immunity       Date:  2009-02-20       Impact factor: 31.745

6.  Betulin induces cytochrome c release and apoptosis in colon cancer cells via NOXA.

Authors:  Zhiyuan Zhou; Chenfang Zhu; Zhongfang Cai; Feng Zhao; Liu He; Xiaolou Lou; Xiaoliang Qi
Journal:  Oncol Lett       Date:  2018-03-06       Impact factor: 2.967

7.  Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells.

Authors:  John A Altin; Stephen R Daley; Jason Howitt; Helen J Rickards; Alison K Batkin; Keisuke Horikawa; Simon J Prasad; Keats A Nelms; Sharad Kumar; Lawren C Wu; Seong-Seng Tan; Matthew C Cook; Christopher C Goodnow
Journal:  Proc Natl Acad Sci U S A       Date:  2014-01-13       Impact factor: 11.205

8.  The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions.

Authors:  Eric E Smith; Harmit S Malik
Journal:  Genome Res       Date:  2009-03-19       Impact factor: 9.043

9.  Dimeric Galectin-8 induces phosphatidylserine exposure in leukocytes through polylactosamine recognition by the C-terminal domain.

Authors:  Sean R Stowell; Connie M Arthur; Kristin A Slanina; John R Horton; David F Smith; Richard D Cummings
Journal:  J Biol Chem       Date:  2008-05-02       Impact factor: 5.157

Review 10.  The rationale for cardiomyocyte resuscitation in myocardial salvage.

Authors:  Gerald W Dorn; Abhinav Diwan
Journal:  J Mol Med (Berl)       Date:  2008-06-19       Impact factor: 4.599

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