Literature DB >> 15718908

Treatment of idiopathic clubfoot utilizing botulinum A toxin: a new method and its short-term outcomes.

Christine M Alvarez1, Stephen J Tredwell, Sean P Keenan, Richard D Beauchamp, Rachel L Choit, Bonita J Sawatzky, Mary A De Vera.   

Abstract

A pivotal point in most clubfoot management protocols is Achilles tendon lengthening or tenotomy to address hindfoot deformity. The effectiveness of botulinum A toxin (BTX-A) in attenuating the function of the triceps surae muscle complex as an alternative to tenotomy was investigated. Fifty-one patients with 73 idiopathic clubfeet were recruited. Outcome measures included surgical rate, Pirani clubfoot score, ankle dorsiflexion with knee in flexion and extension, and recurrences. Patients were divided according to age: group 1 (<30 days old) and group 2 (>30 days and <8 months old). Ankle dorsiflexion in knee flexion and extension remained above 20 degrees and 15 degrees, respectively, and Pirani scores below 0.5 following BTX-A injection for both groups. One of the 51 patients required limited posterior release and 9 patients required repeat manipulation and casting plus or minus BTX-A injection. The use of BTX-A as an adjunctive therapy in the noninvasive approach of manipulation and casting in idiopathic clubfoot is a safe and effective treatment.

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Year:  2005        PMID: 15718908     DOI: 10.1097/01.bpo.0000149861.50400.db

Source DB:  PubMed          Journal:  J Pediatr Orthop        ISSN: 0271-6798            Impact factor:   2.324


  12 in total

1.  [Congenital clubfoot].

Authors:  K Weimann-Stahlschmidt; R Krauspe; B Westhoff
Journal:  Orthopade       Date:  2010-11       Impact factor: 1.087

2.  Effect of botulinum neurotoxin type A (BoNTA) on the morphology and viability of 3T3 murine fibroblasts.

Authors:  Cindy Bandala; Juan Luis Terán-Melo; Maricruz Anaya-Ruiz; Cesar Miguel Mejía-Barradas; Rene Domínguez-Rubio; Paloma De la Garza-Montano; Alfonso Alfaro-Rodríguez; Eleazar Lara-Padilla
Journal:  Int J Clin Exp Pathol       Date:  2015-08-01

Review 3.  [Botulinum toxin therapy in orthopaedics].

Authors:  L Döderlein
Journal:  Orthopade       Date:  2006-01       Impact factor: 1.087

Review 4.  Interventions for congenital talipes equinovarus (clubfoot).

Authors:  Kelly Gray; Verity Pacey; Paul Gibbons; David Little; Joshua Burns
Journal:  Cochrane Database Syst Rev       Date:  2014-08-12

5.  Botulinum toxin type A injections for the management of muscle tightness following total hip arthroplasty: a case series.

Authors:  Anil Bhave; Michael G Zywiel; Slif D Ulrich; Mike S McGrath; Thorsten M Seyler; David R Marker; Ronald E Delanois; Michael A Mont
Journal:  J Orthop Surg Res       Date:  2009-08-26       Impact factor: 2.359

6.  Dynamic Adduction Angle of Forefoot Measured With a Novel Technique And Its Relationship With Functional Outcomes.

Authors:  Nirav Hasmukh Amin; Andre Jakoi; Volpi Ms Alexander; Martin Joseph Morrison; Per Trobisch
Journal:  Malays J Med Sci       Date:  2016-03

7.  Effectiveness and safety of botulinum toxin type a in children with musculoskeletal conditions: what is the current state of evidence?

Authors:  Noémi Dahan-Oliel; Bahar Kasaai; Kathleen Montpetit; Reggie Hamdy
Journal:  Int J Pediatr       Date:  2012-04-05

8.  Early ultrasonographic evaluation of idiopathic clubfeet treated with manipulations, casts, and Botox(®): a double-blind randomized control trial.

Authors:  Alyssa M Howren; Douglas H Jamieson; Christine M Alvarez
Journal:  J Child Orthop       Date:  2015-01-22       Impact factor: 1.548

9.  Interventions for congenital talipes equinovarus (clubfoot).

Authors:  Shadi Bina; Verity Pacey; Elizabeth H Barnes; Joshua Burns; Kelly Gray
Journal:  Cochrane Database Syst Rev       Date:  2020-05-15

10.  The Efficacy and Safety of Fractional CO₂ Laser Combined with Topical Type A Botulinum Toxin for Facial Rejuvenation: A Randomized Controlled Split-Face Study.

Authors:  Jie Zhu; Xi Ji; Min Li; Xiao-e Chen; Juan Liu; Jia-an Zhang; Dan Luo; Bing-rong Zhou
Journal:  Biomed Res Int       Date:  2016-02-22       Impact factor: 3.411

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