Literature DB >> 1571683

Storage of vaccines in the community: weak link in the cold chain?

Y Thakker1, S Woods.   

Abstract

OBJECTIVE: To assess quality of storage of vaccines in the community.
DESIGN: Questionnaire survey of general practices and child health clinics, and monitoring of storage temperatures of selected refrigerators.
SETTING: Central Manchester and Bradford health districts.
SUBJECTS: 45 general practices and five child health clinics, of which 40 (80%) responded. Eight practices were selected for refrigeration monitoring. MAIN OUTCOME MEASURES: Adherence to Department of Health guidelines for vaccine storage, temperature range to which vaccines were exposed over two weeks.
RESULTS: Of the 40 respondents, only 16 were aware of the appropriate storage conditions for the vaccines; eight had minimum and maximum thermometers but only one of these was monitored daily. In six of the eight practices selected for monitoring of refrigeration temperatures the vaccines were exposed to either subzero temperatures (three fridges) or temperatures up to 16 degrees C (three). Two of these were specialised drug storage refrigerators with an incorporated thermostat and external temperature gauges.
CONCLUSION: Vaccines were exposed to temperatures that may reduce their potency. Safe storage of vaccines in the clinics cannot be ensured without adhering to the recommended guidelines. Provision of adequate equipment and training for staff in maintaining the "cold chain" and the use and care of equipment are important components of a successful immunisation programme.

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Year:  1992        PMID: 1571683      PMCID: PMC1881607          DOI: 10.1136/bmj.304.6829.756

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  3 in total

1.  Storage of vaccines in general practice.

Authors:  S Hunter
Journal:  BMJ       Date:  1989-09-09

2.  Transport and storage of vaccines in Hungary: the first cold chain monitor study in Europe.

Authors:  L Lugosi; A Battersby
Journal:  Bull World Health Organ       Date:  1990       Impact factor: 9.408

3.  Mumps arthritis: unusual presentation as adult Still's disease.

Authors:  S C Gordon; C B Lauter
Journal:  Ann Intern Med       Date:  1982-07       Impact factor: 25.391

  3 in total
  19 in total

1.  Storing vaccines at the correct temperature.

Authors:  P Lewis
Journal:  BMJ       Date:  1992-05-09

2.  Graphic-output temperature data loggers for monitoring vaccine refrigeration: implications for pertussis.

Authors:  Patrick McColloster; Carlos Vallbona
Journal:  Am J Public Health       Date:  2010-11-18       Impact factor: 9.308

3.  Storing vaccines at the correct temperature.

Authors:  A Lipp
Journal:  BMJ       Date:  1992-05-30

4.  Vaccine storage and handling. Knowledge and practice in primary care physicians' offices.

Authors:  L Yuan; S Daniels; M Naus; B Brcic
Journal:  Can Fam Physician       Date:  1995-07       Impact factor: 3.275

5.  Assessing cold chain status in a metro city of India: an intervention study.

Authors:  S Mallik; P K Mandal; C Chatterjee; P Ghosh; N Manna; D Chakrabarty; S N Bagchi; S Dasgupta
Journal:  Afr Health Sci       Date:  2011-03       Impact factor: 0.927

6.  Improving vaccine storage in general practice refrigerators.

Authors:  A Jeremijenko; H Kelly; B Sibthorpe; R Attewell
Journal:  BMJ       Date:  1996-06-29

7.  Cold chain storage.

Authors:  M Wilcock
Journal:  Br J Gen Pract       Date:  1996-04       Impact factor: 5.386

8.  Validation of the shake test for detecting freeze damage to adsorbed vaccines.

Authors:  Umit Kartoglu; Nejat Kenan Ozgüler; Lara J Wolfson; Wiesław Kurzatkowski
Journal:  Bull World Health Organ       Date:  2010-02-09       Impact factor: 9.408

9.  Weak link in vaccine cold chain.

Authors:  H Briggs; S Ilett
Journal:  BMJ       Date:  1993-02-27

10.  Stability of vaccines.

Authors:  F E André
Journal:  BMJ       Date:  1993-10-09
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