Literature DB >> 15714588

Much anticipated--the bioactive conformation of epothilone and its binding to tubulin.

Dirk W Heinz1, Wolf-Dieter Schubert, Gerhard Höfle.   

Abstract

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Year:  2005        PMID： 15714588     DOI： 10.1002/anie.200462241

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  13 in total

1.  Weekly ixabepilone administration in heavily pretreated metastatic breast cancer patients.

Authors:  Ellen B Kossoff; Nuttapong Ngamphaiboon; Thomas J Laudico; Tracey L O'Connor
Journal:  Med Oncol       Date:  2010-10-27       Impact factor: 3.064

2.  Design and synthesis of C6-C8 bridged epothilone A.

Authors:  Weiqiang Zhan; Yi Jiang; Peggy J Brodie; David G I Kingston; Dennis C Liotta; James P Snyder
Journal:  Org Lett       Date:  2008-03-21       Impact factor: 6.005

Review 3.  On and around microtubules: an overview.

Authors:  Richard H Wade
Journal:  Mol Biotechnol       Date:  2009-06-30       Impact factor: 2.695

4.  Characterizing the Epothilone Binding Site on β-Tubulin by Photoaffinity Labeling: Identification of β-Tubulin Peptides TARGSQQY and TSRGSQQY as Targets of an Epothilone Photoprobe for Polymerized Tubulin.

Authors:  Adwait R Ranade; LeeAnn Higgins; Todd W Markowski; Nicole Glaser; Dmitry Kashin; Ruoli Bai; Kwon Ho Hong; Ernest Hamel; Gerhard Höfle; Gunda I Georg
Journal:  J Med Chem       Date:  2016-03-17       Impact factor: 7.446

5.  Novel epothilone lactones by an unusual diversion of the Grubbs' metathesis reaction.

Authors:  Qiao-Hong Chen; Thota Ganesh; Yi Jiang; Abhijit Banerjee; Shubhada Sharma; Susan Bane; James P Snyder; David G I Kingston
Journal:  Chem Commun (Camb)       Date:  2010-02-09       Impact factor: 6.222

6.  Biological activity of 4-substituted methoxybenzoyl-aryl-thiazole: an active microtubule inhibitor.

Authors:  Chien-Ming Li; Zhao Wang; Yan Lu; Sunjoo Ahn; Ramesh Narayanan; Jeffrey D Kearbey; Deanna N Parke; Wei Li; Duane D Miller; James T Dalton
Journal:  Cancer Res       Date:  2010-11-16       Impact factor: 12.701

7.  New sources of chemical diversity inspired by biosynthesis: rational design of a potent epothilone analogue.

Authors:  Jeffrey D Frein; Richard E Taylor; Dan L Sackett
Journal:  Org Lett       Date:  2009-08-06       Impact factor: 6.005

Review 8.  Discovery and development of the epothilones : a novel class of antineoplastic drugs.

Authors:  Hans Reichenbach; Gerhard Höfle
Journal:  Drugs R D       Date:  2008

9.  Design, synthesis and biological evaluation of bridged epothilone D analogues.

Authors:  Qiao-Hong Chen; Thota Ganesh; Peggy Brodie; Carla Slebodnick; Yi Jiang; Abhijit Banerjee; Susan Bane; James P Snyder; David G I Kingston
Journal:  Org Biomol Chem       Date:  2008-11-06       Impact factor: 3.876

10.  Management of advanced breast cancer with the epothilone B analog, ixabepilone.

Authors:  William Gradishar
Journal:  Drug Des Devel Ther       Date:  2009-09-21       Impact factor: 4.162
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