BACKGROUND: Adenocarcinomas of the sinonasal cavity are unusual tumors with variable clinical courses. METHODS: We conducted a retrospective chart review between 1980 and 2001. RESULTS: Twenty-four patients (17 men) with sinonasal adenocarcinoma were identified. Nasal obstruction was the most common presenting symptom (75%), and the nose was the most common site of involvement (83%). Eleven tumors (46%) were high grade (grade 3 or 4). Twenty-three patients (95%) underwent an attempt at surgical excision with tumor recurrence or residual disease in seven. Age and tumor grade were associated with overall survival, and tumor grade and intracranial extension were associated with death from disease. CONCLUSIONS: Presentation and treatment for nasal adenocarcinoma varies widely. Some low-grade variants of nasal adenocarcinomas seem to be associated with a more favorable prognosis and, depending on the extent of the tumor, can be treated with less-aggressive therapy. 2005 Wiley Periodicals, Inc.
BACKGROUND:Adenocarcinomas of the sinonasal cavity are unusual tumors with variable clinical courses. METHODS: We conducted a retrospective chart review between 1980 and 2001. RESULTS: Twenty-four patients (17 men) with sinonasal adenocarcinoma were identified. Nasal obstruction was the most common presenting symptom (75%), and the nose was the most common site of involvement (83%). Eleven tumors (46%) were high grade (grade 3 or 4). Twenty-three patients (95%) underwent an attempt at surgical excision with tumor recurrence or residual disease in seven. Age and tumor grade were associated with overall survival, and tumor grade and intracranial extension were associated with death from disease. CONCLUSIONS: Presentation and treatment for nasal adenocarcinoma varies widely. Some low-grade variants of nasal adenocarcinomas seem to be associated with a more favorable prognosis and, depending on the extent of the tumor, can be treated with less-aggressive therapy. 2005 Wiley Periodicals, Inc.
Authors: Susanne Ingrid Mayr; Kamber Hafizovic; Frank Waldfahrer; Heinrich Iro; Birgitta Kütting Journal: Int Arch Occup Environ Health Date: 2009-11-03 Impact factor: 3.015