Literature DB >> 15713858

Renal replacement therapy in the over-80s.

Fiona Ronsberg1, Chris Isles, Keith Simpson, Gordon Prescott.   

Abstract

BACKGROUND: The incidence of chronic renal failure rises dramatically with age, which is no longer seen as a contraindication to treatment. AIM: To characterise Scottish dialysis patients aged 80 years and over at the time of their first treatment and to compare their outcomes with those of patients with other serious illnesses. DESIGN AND METHODS: Retrospective survey of all older patients starting dialysis in Dumfries and Galloway between 1 January 1994 and 31 December 2003, and of all older chronic renal failure patients starting dialysis in Scotland between 1 January 1994 and 31 December 2001. Comparison with 4,565 Scottish Lung Cancer and 14,398 myocardial infarction (MI) patients of similar age.
RESULTS: 213/3,944 Scottish dialysis patients were aged 80 years or over at the time of their first treatment, representing 5.4% of all new patients and 9.2% of all new starts in 2001. Ninety per cent of older patients received haemodialysis as their first mode of renal replacement therapy. The most common diagnosis was chronic renal failure of unknown cause in 41% of cases. Quality of life, measured in a subset of Dumfries patients, suggested similar social functioning and mental health, but poorer physical health than their younger dialysis counterparts. Early mortality was high in all three diagnostic groups. Median survival from 90 days after the start of treatment, registration or hospital admission was 459 days (95% CI, 375, 543) for the older Scottish CRF patients, compared to 141 days (128, 154) for lung cancer and 1242 days (1192, 1292) for MI patients.
CONCLUSIONS: Dialysis can be an effective treatment modality for at least a proportion of octogenarians with end-stage renal failure.

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Year:  2005        PMID: 15713858     DOI: 10.1093/ageing/afi024

Source DB:  PubMed          Journal:  Age Ageing        ISSN: 0002-0729            Impact factor:   10.668


  3 in total

1.  Supportive Care: Comprehensive Conservative Care in End-Stage Kidney Disease.

Authors:  Fliss E M Murtagh; Aine Burns; Olivier Moranne; Rachael L Morton; Saraladevi Naicker
Journal:  Clin J Am Soc Nephrol       Date:  2016-08-10       Impact factor: 8.237

2.  Systematic comprehensive geriatric assessment in elderly patients on chronic dialysis: a cross-sectional comparative and feasibility study.

Authors:  Juliette L Parlevliet; Bianca M Buurman; Marja M Hodac Pannekeet; Els M Boeschoten; Lucia ten Brinke; Marije E Hamaker; Barbara C van Munster; Sophia E de Rooij
Journal:  BMC Nephrol       Date:  2012-05-30       Impact factor: 2.388

3.  Proceedings From the Symposium on Kidney Disease in Older People: Royal Society of Medicine, London, January 19, 2017.

Authors:  Aza Abdulla; Pandora N Wright; Louise E Ross; Hugh Gallagher; Osasuyi Iyasere; Nan Ma; Carol Bartholomew; Karen Lowton; Edwina A Brown
Journal:  Gerontol Geriatr Med       Date:  2017-12-07
  3 in total

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