| Literature DB >> 15713384 |
Li-Qiang Sun1, Katherine Takaki, Jie Chen, Stephen Bertenshaw, Lawrence Iben, Cathy D Mahle, Elaine Ryan, Dedong Wu, Qi Gao, Cen Xu.
Abstract
(R)-2-(4-Phenylbutyl)dihydrobenzofuran derivatives (e.g., 3 and 4) were synthesized as novel melatoninergic ligands with significantly lower vasoconstrictive activity in vitro in the rat tail artery. Binding affinity assays were performed on cloned human MT1 and MT2 receptors stably expressed in NIH3T3 cells.Entities:
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Year: 2005 PMID： 15713384 DOI： 10.1016/j.bmcl.2005.01.015
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823