Literature DB >> 15712066

Fulminant hepatitis B associated with a specific insertion in the basal core promoter region of hepatitis B virus DNA after immunosuppressive treatment.

René Gérolami1, Mireille Henry, Patrick Borentain, Philippe Colson, Danièle Botta, Catherine Tamalet.   

Abstract

We report a case of hepatitis B virus reactivation that occurred after immunosuppressive treatment in a hepatitis B surface antigen-negative patient with detectable antibodies to hepatitis B core antigen and hepatitis B surface antigen. Sequence analysis revealed an 11-bp insertion in the core promoter region of hepatitis virus DNA, creating a novel hepatocyte nuclear factor-1 binding site. This led to enhanced viral replication and fulminant hepatitis.

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Year:  2005        PMID： 15712066     DOI： 10.1086/427146

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  6 in total

1.  Occult hepatitis B virus infection: a case of reactivation in a patient receiving immunosuppressive treatment for allogeneic bone marrow transplantation.

Authors:  Cinzia Lo Giudice; Marina Martinengo; Paolo Pietrasanta; Laura Bocciardo; Cristina Malavasi; Simona Rastelli; Maura Faraci; Gino Tripodi
Journal:  Blood Transfus       Date:  2008-01       Impact factor: 3.443

2.  Epidemiological and virological features of HBV infection in HIV-2 infected patients living in southeastern France.

Authors:  Philippe Colson; Mireille Henry; Anne Motte; Hervé Gallais; Jacques Moreau; Isabelle Poizot-Martin; Catherine Tamalet
Journal:  Eur J Epidemiol       Date:  2006-09-20       Impact factor: 8.082

3.  Prevalence and Characteristics of Basal Core Promoter Mutations in Iran and its Correlation with Acute and Chronic Hepatitis B Infection.

Authors:  Sadegh Nasrollaheian; Gholamreza Farshidfar; Ali Kargar Kheirabad; Hamed Gouklani
Journal:  Electron Physician       Date:  2016-12-25

4.  Characterization of hepatitis B virus with complex structural variations.

Authors:  Kei Fujiwara; Kentaro Matsuura; Kayoko Matsunami; Etsuko Iio; Shunsuke Nojiri
Journal:  BMC Microbiol       Date:  2018-12-03       Impact factor: 3.605

Review 5.  Genomic Diversity of Hepatitis B Virus Infection Associated With Fulminant Hepatitis B Development.

Authors:  Thomas Mina; Samad Amini Bavil Olyaee; Frank Tacke; Piet Maes; Marc Van Ranst; Mahmoud Reza Pourkarim
Journal:  Hepat Mon       Date:  2015-06-23       Impact factor: 0.660

Review 6.  Novel Genetic Rearrangements in Hepatitis B Virus: Complex Structural Variations and Structural Variation Polymorphisms.

Authors:  Kei Fujiwara
Journal:  Viruses       Date:  2021-03-12       Impact factor: 5.048
  6 in total

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