Literature DB >> 15710584

Safety profile of hydroxyurea in the treatment of patients with Philadelphia-negative chronic myeloproliferative disorders.

Maria Luigia Randi, Elisabetta Ruzzon, Guido Luzzatto, Fabiana Tezza, Antonio Girolami, Fabrizio Fabris.   

Abstract

The efficacy of hydroxyurea (HU) in myeloproliferative disorders is well documented. HU controls thrombocytosis both in polycythemia vera (PV) and in essential thrombocythemia (ET), while reducing the risk of thrombosis.1 Despite many anectodal reports, no evaluation of the prevalence and type of side effects of HU exists in large series of patients.

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Year:  2005        PMID： 15710584

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


  6 in total

1.  Coronary artery intervention after cytostatics treatment in unstable angina patient with essential thrombocythemia. A case report and literature review.

Authors:  Hyun Chang; Chi Young Shim; June-Won Cheong; Ju-Yeon Pyo; Young Guk Ko; Donghoon Choi; Yangsoo Jang
Journal:  Korean J Intern Med       Date:  2006-06       Impact factor: 2.884

Review 2.  Advances and challenges in the management of essential thrombocythemia.

Authors:  Gunnar Birgegård
Journal:  Ther Adv Hematol       Date:  2015-06

3.  Hydroxyurea and fetal hemoglobin effect on leg ulcers in patients with sickle cell disease.

Authors:  Seda S Tolu; Andrew Crouch; Jaeun Choi; Qi Gao; Moramaya Reyes-Gil; Ugochi Olivia Ogu; Giacomo Vinces; Caterina P Minniti
Journal:  Ann Hematol       Date:  2022-01-18       Impact factor: 3.673

4.  Acute Lymphoblastic Leukemia Arising in CALR Mutated Essential Thrombocythemia.

Authors:  Stephen E Langabeer; Karl Haslam; David O'Brien; Johanna Kelly; Claire Andrews; Ciara Ryan; Richard Flavin; Patrick J Hayden; Christopher L Bacon
Journal:  Case Rep Hematol       Date:  2016-01-21

5.  Hydroxyurea Induces a Stress Response That Alters DNA Replication and Nucleotide Metabolism in Bacillus subtilis.

Authors:  Katherine J Wozniak; Lyle A Simmons
Journal:  J Bacteriol       Date:  2021-07-08       Impact factor: 3.490

6.  Treatment Patterns and Blood Counts in Patients With Polycythemia Vera Treated With Hydroxyurea in the United States: An Analysis From the REVEAL Study.

Authors:  Michael R Grunwald; David J Kuter; Ivy Altomare; John M Burke; Aaron T Gerds; Mark A Walshauser; Michael R Savona; Brady Stein; Stephen T Oh; Philomena Colucci; Shreekant Parasuraman; Dilan Paranagama; Ruben Mesa
Journal:  Clin Lymphoma Myeloma Leuk       Date:  2019-09-30
  6 in total

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