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Literature DB >> 15709124

Differential chemosensitivity of tumor components in a malignant oligodendroglioma: assessment with diffusion-weighted, perfusion-weighted, and serial volumetric MR imaging.

Hans Rolf Jäger¹, Adam D Waldman, Christopher Benton, Nicholas Fox, Jeremy Rees.

Abstract

We report the case of malignant oligodendroglioma in a 36-year-old man who underwent diffusion-weighted, perfusion-weighted, and volumetric MR imaging before and after PCV (procarbazine, CCNU, vincristine) chemotherapy. The tumor regions exhibiting a low apparent diffusion coefficient and increased relative cerebral blood volume showed a marked response to chemotherapy and dramatic decrease in volume, whereas the remaining tumor regions showed little change. Diffusion-weighted and perfusion-weighted MR imaging may be helpful in predicting chemosensitivity of glial tumors.

Entities: Chemical

Mesh：

Year: 2005 PMID： 15709124 PMCID： PMC7974071

Source DB: PubMed Journal: AJNR Am J Neuroradiol ISSN： 0195-6108 Impact factor: 3.825

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