Literature DB >> 15709093

Phase II study of oral S-1 plus irinotecan in patients with advanced colorectal cancer: Hokkaido Gastrointestinal Cancer Study Group HGCSG0302.

Yoshito Komatsu1, Satoshi Yuuki, Nozomu Fuse, Masaaki Takei, Takashi Kato, Takuto Miyagishima, Mineo Kudo, Yasuyuki Kunieda, Miki Tateyama, Osamu Wakahama, Takashi Meguro, Hiroko Ohizumi, Maso Watanabe, Hirotoshi Akita, Yu Sakata, Masahiro Asaka.   

Abstract

We have previously reported on phase I/II studies of irinotecan plus S-1 therapy for advanced gastric cancer. Based on the safety and efficacy data that were obtained, this phase II study was planned to assess the efficacy of irinotecan plus S-1 for patients with advanced colorectral cancer. A total of 40 patients are enrolled at 13 medical institutions. The objective of this study was to establish a useful chemotherapy regimen for an out-patient setting.

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Year:  2005        PMID： 15709093     DOI： 10.1093/jjco/hyi025

Source DB:  PubMed          Journal:  Jpn J Clin Oncol        ISSN： 0368-2811            Impact factor:   3.019


  2 in total

1.  A case of bone metastasis of colon cancer that markedly responded to S-1/CPT-11 combination chemotherapy and became curable by resection.

Authors:  Kazunari Mado; Yukimoto Ishii; Takero Mazaki; Masaya Ushio; Hideki Masuda; Tadatoshi Takayama
Journal:  World J Surg Oncol       Date:  2006-01-18       Impact factor: 2.754

2.  Phase I/II study of S-1 combined with irinotecan for metastatic advanced gastric cancer.

Authors:  M Inokuchi; T Yamashita; H Yamada; K Kojima; W Ichikawa; Z Nihei; T Kawano; K Sugihara
Journal:  Br J Cancer       Date:  2006-04-24       Impact factor: 7.640
  2 in total

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