Literature DB >> 15708936

Ethical and practical issues in conducting clinical trials in psoriasis and psoriatic arthritis.

A Kavanaugh1.   

Abstract

Ethical considerations are inexorably intertwined with the conduct of clinical research. As a result of progress in immunology and biotechnology, several potent novel therapeutics have recently emerged for the treatment of patients with various immunologically driven systemic inflammatory conditions, including psoriasis and psoriatic arthritis. Because of these developments, there is a need to continually assess the design of current and future research studies so that they may be conducted in the optimal and most ethical manner.

Entities:  

Keywords:  Biomedical and Behavioral Research

Mesh：

Year:  2005        PMID： 15708936      PMCID： PMC1766869          DOI： 10.1136/ard.2004.030817

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  12 in total

Review 1.  Publication bias: a brief review for clinicians.

Authors:  V M Montori; M Smieja; G H Guyatt
Journal:  Mayo Clin Proc       Date:  2000-12       Impact factor: 7.616

Review 2.  Moving from compliance to conscience: why we can and should improve on the ethics of clinical research.

Authors:  J P Kahn; A C Mastroianni
Journal:  Arch Intern Med       Date:  2001-04-09

3.  Uneasy alliance--clinical investigators and the pharmaceutical industry.

Authors:  T Bodenheimer
Journal:  N Engl J Med       Date:  2000-05-18       Impact factor: 91.245

4.  Ethical issues in the design and conduct of clinical trials in developing countries.

Authors:  H T Shapiro; E M Meslin
Journal:  N Engl J Med       Date:  2001-07-12       Impact factor: 91.245

Review 5.  Industry-sponsored clinical research: a double-edged sword.

Authors:  J S Montaner; M V O'Shaughnessy; M T Schechter
Journal:  Lancet       Date:  2001-12-01       Impact factor: 79.321

6.  Placebo-controlled trials and the Declaration of Helsinki.

Authors:  John A Lewis; Bertil Jonsson; Gottfried Kreutz; Cristina Sampaio; Barbara van Zwieten-Boot
Journal:  Lancet       Date:  2002-04-13       Impact factor: 79.321

7.  The uncertainty principle and industry-sponsored research.

Authors:  B Djulbegovic; M Lacevic; A Cantor; K K Fields; C L Bennett; J R Adams; N M Kuderer; G H Lyman
Journal:  Lancet       Date:  2000-08-19       Impact factor: 79.321

8.  Medical ethics and controlled trials.

Authors:  A B HILL
Journal:  Br Med J       Date:  1963-04-20

9.  The continuing unethical use of placebo controls.

Authors:  K J Rothman; K B Michels
Journal:  N Engl J Med       Date:  1994-08-11       Impact factor: 91.245

Review 10.  Placebo effect in double-blind clinical trials: a review of interactions with medications.

Authors:  J Kleijnen; A J de Craen; J van Everdingen; L Krol
Journal:  Lancet       Date:  1994-11-12       Impact factor: 79.321
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  3 in total

1.  The Infliximab Multinational Psoriatic Arthritis Controlled Trial (IMPACT): results of radiographic analyses after 1 year.

Authors:  A Kavanaugh; C E Antoni; D Gladman; S Wassenberg; B Zhou; A Beutler; G Keenan; G Burmester; D E Furst; M H Weisman; J R Kalden; J Smolen; D van der Heijde
Journal:  Ann Rheum Dis       Date:  2006-01-26       Impact factor: 19.103

2.  Comparison of Drug Discontinuation, Effectiveness, and Safety Between Clinical Trial Eligible and Ineligible Patients in BADBIR.

Authors:  Kayleigh J Mason; Jonathan N W N Barker; Catherine H Smith; Philip J Hampton; Mark Lunt; Kathleen McElhone; Richard B Warren; Zenas Z N Yiu; Christopher E M Griffiths; A David Burden
Journal:  JAMA Dermatol       Date:  2018-05-01       Impact factor: 10.282

3.  A pilot study assessing the effect of prolonged administration of high daily doses of vitamin D on the clinical course of vitiligo and psoriasis.

Authors:  Danilo C Finamor; Rita Sinigaglia-Coimbra; Luiz C M Neves; Marcia Gutierrez; Jeferson J Silva; Lucas D Torres; Fernanda Surano; Domingos J Neto; Neil F Novo; Yara Juliano; Antonio C Lopes; Cicero Galli Coimbra
Journal:  Dermatoendocrinol       Date:  2013-01-01
  3 in total

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