Literature DB >> 1570893

Segregation and linkage analysis.

R C Elston1.   

Abstract

Computer programs are available in the software package SAGE to perform a variety of segregation and linkage analyses used by human geneticists. These methods are designed specifically to uncover major gene segregation in pedigree data coming from non-inbred populations. With the aid of a closely linked polymorphic marker, they can detect a locus that contributes as little as 10% to the variation of a quantitative trait in a pedigree sample of several hundred individuals.

Entities:  

Mesh：

Year:  1992        PMID： 1570893

Source DB:  PubMed          Journal:  Anim Genet        ISSN： 0268-9146            Impact factor:   3.169


  4 in total

Review 1.  Linkage analysis in the next-generation sequencing era.

Authors:  Joan E Bailey-Wilson; Alexander F Wilson
Journal:  Hum Hered       Date:  2011-12-23       Impact factor: 0.444

2.  Allelic frequencies and heterozygosities of microsatellite markers covering the whole genome in the Korean.

Authors:  M-H Park; K-S Kim; H-J Lee; Y-M Cho; H-K Lee; K-S Park; D-J Shin; Y Jang; K-J Kim; J Jung; H-L Kim; B Oh; J-Y Lee
Journal:  J Hum Genet       Date:  2008-02-08       Impact factor: 3.172

3.  Aggressive periodontitis is likely influenced by a few small effect genes.

Authors:  Flavia M de Carvalho; Eduardo M B Tinoco; Manika Govil; Mary L Marazita; Alexandre R Vieira
Journal:  J Clin Periodontol       Date:  2009-04-22       Impact factor: 8.728

4.  Genomewide linkage survey of nicotine dependence phenotypes.

Authors:  Patrick F Sullivan; Po-Hsiu Kuo; B Todd Webb; Michael C Neale; Jen Vittum; Helena Furberg; Dermot Walsh; Diana G Patterson; Brien Riley; Carol A Prescott; Kenneth S Kendler
Journal:  Drug Alcohol Depend       Date:  2007-11-19       Impact factor: 4.492
  4 in total

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