Literature DB >> 15706458

Use of nonprohibited hallucinogenic plants: increasing relevance for public health? A case report and literature review on the consumption of Salvia divinorum (Diviner's Sage).

R Bücheler1, C H Gleiter, P Schwoerer, I Gaertner.   

Abstract

INTRODUCTION: : We want to call attention to a mint plant, called diviner's sage ( Salvia divinorum), originally used in shamanic ceremonies of the Mazatec Indians of Mexico. On numerous websites of the internet, this ancient herbal drug and its extracts are offered as a legal means of widening individual awareness. Regarding its dose-response relationship, the active ingredient, salvinorin A, is one of the most potent naturally occurring hallucinogens. Laws on controlled substances, except for Finland, Denmark and Australia, do not prohibit cultivating, consuming or dealing with Salvia divinorum. Ingestion by smoking, vaporising or chewing, induces a short-lived inebriant state with intense, bizarre feelings of depersonalization. This article wants to be a signal for physicians or psychotherapists to take Salvia into consideration, when exploring young people for drug use.
METHODS: We report the individual perceptions of a young man consuming Salvia divinorum. We review the scarce scientific literature and consider relevant internet websites. DISCUSSION: We define open issues for further investigations and try to discuss why Salvia divinorum may be of interest for teenagers and young adults in Europe.

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Year:  2005        PMID: 15706458     DOI: 10.1055/s-2005-837763

Source DB:  PubMed          Journal:  Pharmacopsychiatry        ISSN: 0176-3679            Impact factor:   5.788


  10 in total

1.  Use of Salvia divinorum in a nationally representative sample.

Authors:  Brian E Perron; Brian K Ahmedani; Michael G Vaughn; Joseph E Glass; Arnelyn Abdon; Li-Tzy Wu
Journal:  Am J Drug Alcohol Abuse       Date:  2011-08-11       Impact factor: 3.829

Review 2.  Kappa-opioid ligands in the study and treatment of mood disorders.

Authors:  William A Carlezon; Cécile Béguin; Allison T Knoll; Bruce M Cohen
Journal:  Pharmacol Ther       Date:  2009-06-02       Impact factor: 12.310

3.  Novel Drugs of Abuse: A Snapshot of an Evolving Marketplace.

Authors:  Ryan Vandrey; Matthew W Johnson; Patrick S Johnson; Miral A Khalil
Journal:  Adolesc Psychiatry (Hilversum)       Date:  2013-04

4.  From divination to madness: features of acute intoxication with Salvia use.

Authors:  Munidasa Winslow; Rathi Mahendran
Journal:  Singapore Med J       Date:  2014-04       Impact factor: 1.858

5.  Hallucinatory and rewarding effect of salvinorin A in zebrafish: kappa-opioid and CB1-cannabinoid receptor involvement.

Authors:  Daniela Braida; Valeria Limonta; Simona Pegorini; Alessia Zani; Chiara Guerini-Rocco; Enzo Gori; Mariaelvina Sala
Journal:  Psychopharmacology (Berl)       Date:  2007-01-12       Impact factor: 4.530

6.  Human psychopharmacology and dose-effects of salvinorin A, a kappa opioid agonist hallucinogen present in the plant Salvia divinorum.

Authors:  Matthew W Johnson; Katherine A MacLean; Chad J Reissig; Thomas E Prisinzano; Roland R Griffiths
Journal:  Drug Alcohol Depend       Date:  2010-12-04       Impact factor: 4.492

Review 7.  Psychiatric neural networks and neuropharmacology: Selected advances and novel implications.

Authors:  Abdelaziz Ghanemi
Journal:  Saudi Pharm J       Date:  2013-02-10       Impact factor: 4.330

8.  Recent national trends in Salvia divinorum use and substance-use disorders among recent and former Salvia divinorum users compared with nonusers.

Authors:  Li-Tzy Wu; George E Woody; Chongming Yang; Jih-Heng Li; Dan G Blazer
Journal:  Subst Abuse Rehabil       Date:  2011-04

9.  Salvinorin-A Induces Intense Dissociative Effects, Blocking External Sensory Perception and Modulating Interoception and Sense of Body Ownership in Humans.

Authors:  Ana Elda Maqueda; Marta Valle; Peter H Addy; Rosa Maria Antonijoan; Montserrat Puntes; Jimena Coimbra; Maria Rosa Ballester; Maite Garrido; Mireia González; Judit Claramunt; Steven Barker; Matthew W Johnson; Roland R Griffiths; Jordi Riba
Journal:  Int J Neuropsychopharmacol       Date:  2015-06-05       Impact factor: 5.176

Review 10.  Pharmacokinetics and Pharmacodynamics of Salvinorin A and Salvia divinorum: Clinical and Forensic Aspects.

Authors:  Andreia Machado Brito-da-Costa; Diana Dias-da-Silva; Nelson G M Gomes; Ricardo Jorge Dinis-Oliveira; Áurea Madureira-Carvalho
Journal:  Pharmaceuticals (Basel)       Date:  2021-02-03
  10 in total

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