Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Rephrasing anaphase: separase FEARs shugoshin.

Literature DB >> 15703941

Rephrasing anaphase: separase FEARs shugoshin.

Olaf Stemmann¹, Dominik Boos, Ingo H Gorr.

Abstract

Cleavage of the ring-like cohesin complex by separase triggers segregation of sister chromatids in anaphase. This simplistic model has recently been extended by exciting discoveries on three levels: regulation of anaphase by posttranslational modifications and the cohesin protector shugoshin; non-proteolytic roles of separase; and cohesin-independent linkage of sister chromatids.

Entities: Gene

Mesh：

Substances：

Year: 2005 PMID： 15703941 DOI： 10.1007/s00412-005-0331-y

Source DB: PubMed Journal: Chromosoma ISSN： 0009-5915 Impact factor: 4.316

86 in total

1. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast.

Authors: F Uhlmann; D Wernic; M A Poupart; E V Koonin; K Nasmyth
Journal: Cell Date: 2000-10-27 Impact factor: 41.582

2. Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage.

Authors: G Alexandru; W Zachariae; A Schleiffer; K Nasmyth
Journal: EMBO J Date: 1999-05-17 Impact factor: 11.598

3. Chromosomal cohesin forms a ring.

Authors: Stephan Gruber; Christian H Haering; Kim Nasmyth
Journal: Cell Date: 2003-03-21 Impact factor: 41.582

4. Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase.

Authors: Frank Stegmeier; Rosella Visintin; Angelika Amon
Journal: Cell Date: 2002-01-25 Impact factor: 41.582

5. Sequence of centromere separation: analysis of mitotic chromosomes in man.

Authors: B K Vig
Journal: Hum Genet Date: 1981 Impact factor: 4.132

6. Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase.

Authors: Matt Sullivan; Toru Higuchi; Vittorio L Katis; Frank Uhlmann
Journal: Cell Date: 2004-05-14 Impact factor: 41.582

7. Separase regulates INCENP-Aurora B anaphase spindle function through Cdc14.

Authors: Gislene Pereira; Elmar Schiebel
Journal: Science Date: 2003-11-06 Impact factor: 47.728

8. Maintenance of cohesin at centromeres after meiosis I in budding yeast requires a kinetochore-associated protein related to MEI-S332.

Authors: Vittorio L Katis; Marta Galova; Kirsten P Rabitsch; Juraj Gregan; Kim Nasmyth
Journal: Curr Biol Date: 2004-04-06 Impact factor: 10.834

Rephrasing anaphase: separase FEARs shugoshin.

1. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast.

2. Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage.

3. Chromosomal cohesin forms a ring.

4. Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase.

5. Sequence of centromere separation: analysis of mitotic chromosomes in man.

6. Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase.

7. Separase regulates INCENP-Aurora B anaphase spindle function through Cdc14.

8. Maintenance of cohesin at centromeres after meiosis I in budding yeast requires a kinetochore-associated protein related to MEI-S332.

9. APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit.

10. The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly.

1. A snapshot of the Ixodes scapularis degradome.

2. Arabidopsis separase AESP is essential for embryo development and the release of cohesin during meiosis.

3. Securin is not required for chromosomal stability in human cells.