Literature DB >> 15703799

Asymmetric cyclopropane synthesis via phosphine oxide mediated cascade reactions.

Thomas Boesen1, David J Fox, Warren Galloway, Daniel Sejer Pedersen, Charles R Tyzack, Stuart Warren.   

Abstract

A silyloxy-THF has been converted into a cyclopropane containing three stereocentres as mixture of diastereoisomers. The mechanism of the reaction has been established and the source of stereochemical leakage proposed. An alternative stereospecific cascade reaction has been discovered.

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Year:  2005        PMID: 15703799     DOI: 10.1039/b413500h

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

1.  Crystal structures of 1-(4-chloro-phen-yl)-2-(di-phenyl-phosphor-yl)ethan-1-one and 1-(di-phenyl-phosphor-yl)-3,3-di-methyl-butan-2-one.

Authors:  Erin G Leach; Alyssa A Kulesza; Richard J Staples; Shannon M Biros
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-04-22
  1 in total

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