Literature DB >> 15703484

Helper-dependent adenoviral vectors for gene therapy.

Donna J Palmer1, Philip Ng.   

Abstract

Helper-dependent adenoviral vectors possess a number of characteristics that make them attractive gene therapy vectors. These vectors are completely devoid of viral coding sequences and are able to mediate high-efficiency transduction in vivo to direct sustain high-level transgene expression with negligible chronic toxicity. This review focuses on advances in helper-dependent adenoviral vector technology, selected examples of in vivo studies of particular interest, and the issue of vector-mediated acute toxicity.

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Year:  2005        PMID： 15703484     DOI： 10.1089/hum.2005.16.1

Source DB:  PubMed          Journal:  Hum Gene Ther        ISSN： 1043-0342            Impact factor:   5.695


  59 in total

1.  Efficient and accurate homologous recombination in hESCs and hiPSCs using helper-dependent adenoviral vectors.

Authors:  Emi Aizawa; Yuka Hirabayashi; Yuzuru Iwanaga; Keiichiro Suzuki; Kenji Sakurai; Miho Shimoji; Kazuhiro Aiba; Tamaki Wada; Norie Tooi; Eihachiro Kawase; Hirofumi Suemori; Norio Nakatsuji; Kohnosuke Mitani
Journal:  Mol Ther       Date:  2011-12-06       Impact factor: 11.454

Review 2.  Gene therapy in the cornea: 2005--present.

Authors:  Rajiv R Mohan; Jonathan C K Tovey; Ajay Sharma; Ashish Tandon
Journal:  Prog Retin Eye Res       Date:  2011-09-28       Impact factor: 21.198

3.  Gene therapy to the kidney using viral vectors.

Authors:  Talha Akbulut; Frank Park
Journal:  Paidiatrike       Date:  2008

Review 4.  Cell and gene therapy for genetic diseases: inherited disorders affecting the lung and those mimicking sudden infant death syndrome.

Authors:  Allison M Keeler; Terence R Flotte
Journal:  Hum Gene Ther       Date:  2012-06       Impact factor: 5.695

5.  BTK gene targeting by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vector.

Authors:  H Yamamoto; M Ishimura; M Ochiai; H Takada; K Kusuhara; Y Nakatsu; T Tsuzuki; K Mitani; T Hara
Journal:  Gene Ther       Date:  2015-08-17       Impact factor: 5.250

6.  Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo.

Authors:  Zachary C Hartman; Anne Kiang; Ruth S Everett; Delila Serra; Xiao Y Yang; Timothy M Clay; Andrea Amalfitano
Journal:  J Virol       Date:  2006-11-22       Impact factor: 5.103

Review 7.  Current advances and future challenges in Adenoviral vector biology and targeting.

Authors:  Samuel K Campos; Michael A Barry
Journal:  Curr Gene Ther       Date:  2007-06       Impact factor: 4.391

8.  Overexpression of endothelial nitric oxide synthase improves endothelium-dependent vasodilation in arteries infused with helper-dependent adenovirus.

Authors:  Bo Jiang; Liang Du; Rowan Flynn; Nagadhara Dronadula; Jingwan Zhang; Francis Kim; David Dichek
Journal:  Hum Gene Ther       Date:  2012-09-24       Impact factor: 5.695

9.  Combinatorial Prg4 and Il-1ra Gene Therapy Protects Against Hyperalgesia and Cartilage Degeneration in Post-Traumatic Osteoarthritis.

Authors:  Adrianne Stone; Matthew W Grol; Merry Z C Ruan; Brian Dawson; Yuqing Chen; Ming-Ming Jiang; I-Wen Song; Prathap Jayaram; Racel Cela; Francis Gannon; Brendan H L Lee
Journal:  Hum Gene Ther       Date:  2018-10-17       Impact factor: 5.695

10.  Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells.

Authors:  Miho Murakami; Hideyo Ugai; Natalya Belousova; Alexander Pereboev; Paul Dent; Paul B Fisher; Maaike Everts; David T Curiel
Journal:  Prostate       Date:  2010-03-01       Impact factor: 4.104
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