Literature DB >> 15702688

Estimates of prevalence of hip dysplasia in Golden Retrievers and Rottweilers and the influence of bias on published prevalence figures.

Erin R Paster1, Elizabeth LaFond, Darryl N Biery, Alisa Iriye, Thomas P Gregor, Frances S Shofer, Gail K Smith.   

Abstract

OBJECTIVE: To estimate prevalence of canine hip dysplasia (CHD) in Golden Retrievers and Rottweilers and identify sources of bias in published reports.
DESIGN: Prospective study. ANIMALS: 200 clinically normal Golden Retrievers and 140 clinically normal Rottweilers between 24 and 60 months of age referred for hip evaluation (group 1) and 93 clinically normal dogs evaluated for Orthopedic Foundation for Animals (OFA) hip certification (group 2). PROCEDURE: Hip-extended pelvic radiographs from group 1 dogs were screened for CHD. Radiographs were evaluated twice; the first interpretation used an OFA-type subjective 7-point scoring system, and the second included the caudolateral curvilinear osteophyte as an additional sign of degenerative joint disease. The OFA submission rate of group 2 dogs was determined from the number of official reports returned from the OFA.
RESULTS: Prevalence of CHD in Golden Retrievers ranged from 53% to 73% and in Rottweilers ranged from 41% to 69%. Among dogs referred for OFA evaluation, radiographs from 49 (53%) were submitted to OFA. Of submitted radiographs, 45 (92%) were normal; of radiographs not submitted, 22 (50%) were normal. Radiographs with normal-appearing hips were 8.2 times as likely to be submitted to the OFA. Compared with Golden Retrievers, Rottweiler radiographs were significantly more likely to be submitted for OFA certification. CONCLUSIONS AND CLINICAL RELEVANCE: Prevalence of CHD in these 2 breeds may be much higher than previously reported in the United States. Results suggest substantial bias in the OFA database, which causes lower estimates of prevalence of CHD.

Entities:  

Mesh:

Year:  2005        PMID: 15702688     DOI: 10.2460/javma.2005.226.387

Source DB:  PubMed          Journal:  J Am Vet Med Assoc        ISSN: 0003-1488            Impact factor:   1.936


  15 in total

Review 1.  Empowering international canine inherited disorder management.

Authors:  Bethany J Wilson; Claire M Wade
Journal:  Mamm Genome       Date:  2011-11-12       Impact factor: 2.957

2.  The relationship between the size of caudolateral curvilinear osteophyte of the canine femoral neck and the radiographic view.

Authors:  Miori Kishimoto; Sa-Hun Pae; Naoyoshi Muroya; Hirokazu Watarai; Hiroshi Anzai; Ki-Ja Lee; Junichiro Shimizu; Motoki Sasaki; Kazutaka Yamada
Journal:  J Vet Sci       Date:  2010-03       Impact factor: 1.672

3.  Estimated breeding values for canine hip dysplasia radiographic traits in a cohort of Australian German Shepherd dogs.

Authors:  Bethany J Wilson; Frank W Nicholas; John W James; Claire M Wade; Peter C Thomson
Journal:  PLoS One       Date:  2013-10-29       Impact factor: 3.240

4.  Radiographic evaluation of early periprosthetic acetabular bone contrast and prosthetic head acetabular coverage after uncemented and cemented total hip prosthesis in dogs.

Authors:  Ayman A Mostafa; Karin Lucas; Ingo Nolte; Patrick Wefstaedt
Journal:  BMC Vet Res       Date:  2016-12-03       Impact factor: 2.741

5.  A randomized, double-blind, prospective, placebo-controlled study of the efficacy of a diet supplemented with curcuminoids extract, hydrolyzed collagen and green tea extract in owner's dogs with osteoarthritis.

Authors:  Fanny Comblain; Nicolas Barthélémy; Michael Lefèbvre; Cédric Schwartz; Isabelle Lesponne; Samuel Serisier; Alexandre Feugier; Marc Balligand; Yves Henrotin
Journal:  BMC Vet Res       Date:  2017-12-20       Impact factor: 2.741

6.  Long-term genetic selection reduced prevalence of hip and elbow dysplasia in 60 dog breeds.

Authors:  A M Oberbauer; G G Keller; T R Famula
Journal:  PLoS One       Date:  2017-02-24       Impact factor: 3.240

7.  Genetic improvement of hip-extended scores in 3 breeds of guide dogs using estimated breeding values: Notable progress but more improvement is needed.

Authors:  Eldin A Leighton; Dolores Holle; Darryl N Biery; Thomas P Gregor; Mischa B McDonald-Lynch; Mandy L Wallace; Jennifer K Reagan; Gail K Smith
Journal:  PLoS One       Date:  2019-02-22       Impact factor: 3.240

8.  Effect of analgesic therapy on clinical outcome measures in a randomized controlled trial using client-owned dogs with hip osteoarthritis.

Authors:  Sarah Malek; Susannah J Sample; Zeev Schwartz; Brett Nemke; Peer B Jacobson; Elizabeth M Cozzi; Susan L Schaefer; Jason A Bleedorn; Gerianne Holzman; Peter Muir
Journal:  BMC Vet Res       Date:  2012-10-04       Impact factor: 2.741

9.  Expression stability of commonly used reference genes in canine articular connective tissues.

Authors:  Duncan Ayers; Dylan N Clements; Fiona Salway; Philip J R Day
Journal:  BMC Vet Res       Date:  2007-05-07       Impact factor: 2.741

Review 10.  Emerging insights into the genetic basis of canine hip dysplasia.

Authors:  Mário Ginja; Ana Rita Gaspar; Catarina Ginja
Journal:  Vet Med (Auckl)       Date:  2015-05-20
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.