Literature DB >> 15702411

Severe hyperhomocysteinaemia and 5-oxoprolinuria secondary to antiproliferative and antimicrobial drug treatment.

B Schwahn1, G Kameda, R Wessalowski, E Mayatepek.   

Abstract

A hitherto healthy 7-year-old girl underwent antiproliferative and antibiotic treatment owing to the diagnosis of T-cell lymphoma and concomitant bacterial infection. She developed an encephalopathic crisis associated with metabolic acidosis, hyponatraemia and severe hyperhomocysteinaemia and 5-oxoprolinuria. Laboratory tests normalized completely after recovery. Primary defects in glutathione metabolism could be excluded.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 15702411     DOI: 10.1007/s10545-005-5084-5

Source DB:  PubMed          Journal:  J Inherit Metab Dis        ISSN: 0141-8955            Impact factor:   4.982


  5 in total

1.  5-Oxoprolinuria in patients with and without defects in the gamma-glutamyl cycle.

Authors:  E Mayatepek
Journal:  Eur J Pediatr       Date:  1999-03       Impact factor: 3.183

2.  Transient 5-oxoprolinuria (pyroglutamic aciduria) with systemic acidosis in an adult receiving antibiotic therapy.

Authors:  B L Croal; A C Glen; C J Kelly; R W Logan
Journal:  Clin Chem       Date:  1998-02       Impact factor: 8.327

Review 3.  Patients with genetic defects in the gamma-glutamyl cycle.

Authors:  E Ristoff; A Larsson
Journal:  Chem Biol Interact       Date:  1998-04-24       Impact factor: 5.192

4.  Transient 5-oxoprolinuria and high anion gap metabolic acidosis: clinical and biochemical findings in eleven subjects.

Authors:  J J Pitt; S Hauser
Journal:  Clin Chem       Date:  1998-07       Impact factor: 8.327

5.  Accumulation of pyroglutamic acid (5-oxoproline) in homocystinuria.

Authors:  O Stokke; S Marstein; E Jellum; S O Lie
Journal:  Scand J Clin Lab Invest       Date:  1982-06       Impact factor: 1.713

  5 in total
  3 in total

1.  5-Oxoprolinuria in Heterozygous Patients for 5-Oxoprolinase (OPLAH) Missense Changes.

Authors:  Eduardo Calpena; Mercedes Casado; Dolores Martínez-Rubio; Andrés Nascimento; Jaume Colomer; Eva Gargallo; Angels García-Cazorla; Francesc Palau; Rafael Artuch; Carmen Espinós
Journal:  JIMD Rep       Date:  2012-07-06

2.  New insights into the genetics of 5-oxoprolinase deficiency and further evidence that it is a benign biochemical condition.

Authors:  Eduardo Calpena; Anup Arunrao Deshpande; Sufin Yap; Akhilesh Kumar; Nigel J Manning; Anand K Bachhawat; Carmen Espinós
Journal:  Eur J Pediatr       Date:  2014-08-17       Impact factor: 3.183

3.  Age-associated perturbations in glutathione synthesis in mouse liver.

Authors:  Dikran Toroser; Rajindar S Sohal
Journal:  Biochem J       Date:  2007-08-01       Impact factor: 3.857

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.