Literature DB >> 15700747

Biological activity of parrodienes, a new class of polyunsaturated linear aldehydes similar to carotenoids.

E Pini1, A Bertelli, R Stradi, M Falchi.   

Abstract

A new chemical named parrodienes has been extracted from parrots' plumage. From the chemical point of view, parrodienes are polyunsaturated aldehydes similar to carotenoids. On the basis of this similarity we organized some biological experiments to evaluate the inhibition of lipoperoxidation of cell membranes induced by CCl4, protection against ultraviolet rays, anti-inflammatory activity and protection from an increase of ornithine-decarboxylase as marker of tumoral skin alteration. The results of these experiments showed that unsaturated dienes (parrodienes) play an important role on the inhibition and prevention of many biological processes that are at the basis of different pathological disorders.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 15700747

Source DB:  PubMed          Journal:  Drugs Exp Clin Res        ISSN: 0378-6501


  5 in total

1.  The activation of PPARγ by 2,4,6-Octatrienoic acid protects human keratinocytes from UVR-induced damages.

Authors:  Enrica Flori; Arianna Mastrofrancesco; Daniela Kovacs; Barbara Bellei; Stefania Briganti; Vittoria Maresca; Giorgia Cardinali; Mauro Picardo
Journal:  Sci Rep       Date:  2017-08-23       Impact factor: 4.379

2.  Protective effects of sunscreen (50+) and octatrienoic acid 0.1% in actinic keratosis and UV damages.

Authors:  Daniela Pinto; Anna Trink; Giammaria Giuliani; Fabio Rinaldi
Journal:  J Investig Med       Date:  2021-09-16       Impact factor: 2.895

3.  A Randomized Double-Blind Parallel-Group Study to Evaluate the Long-Term Effects of a Medical Device Containing 0.3% Octatrienoic Acid in the Treatment of Grade III Actinic Keratosis.

Authors:  Graziella Babino; Stefano Caccavale; Daniela Pinto; Anna Trink; Giammaria Giuliani; Fabio Rinaldi; Giuseppe Argenziano
Journal:  Dermatol Ther (Heidelb)       Date:  2021-09-02

4.  Immune investment is explained by sexual selection and pace-of-life, but not longevity in parrots (Psittaciformes).

Authors:  Darryl B Edwards
Journal:  PLoS One       Date:  2012-12-27       Impact factor: 3.240

5.  Modulation of PPARγ provides new insights in a stress induced premature senescence model.

Authors:  Stefania Briganti; Enrica Flori; Barbara Bellei; Mauro Picardo
Journal:  PLoS One       Date:  2014-08-07       Impact factor: 3.240

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.