Literature DB >> 15699909

[Choroid metastases revealing pulmonary adenocarcioma resolved with chemotherapy].

M H Battikh1, S Ben Yahia, M M Ben Sayah, A Maatallah, S Joobeur, N Rouatbi, M Khairallah, A El Kamel.   

Abstract

Lung cancer is the leading cause of choroidal metastasis in men, but choroidal metastasis is rarely inaugural. With the advent of new generations of chemotherapy molecules non-small-cell lung cancer (NSCLC) has become more chemosensitive. Choroidal metastasis may respond to chemotherapy. We report a case of a 52-year-old men who developed choroidal metastasis revealing pulmonary adenocarcinoma confirmed by the bronchial biopsy. Systemic chemotherapy using gemcitabine-cisplatin led to total involution of the choroidal metastasis with improvement of the visual acuity in one eye and stabilization in the other. Systematic search for lung cancer is required in patients presenting choroidal metastasis. If compatible with the patient's general status, histologically-adapted chemotherapy must be instituted. This approach can avoid the use of radiotherapy and therefore deterioration of visual acuity after radiation.

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Mesh:

Year:  2004        PMID: 15699909     DOI: 10.1016/s0761-8417(04)72149-5

Source DB:  PubMed          Journal:  Rev Pneumol Clin        ISSN: 0761-8417


  7 in total

Review 1.  Emerging treatments for choroidal metastases.

Authors:  Connie J Chen; Allison N McCoy; Julie Brahmer; James T Handa
Journal:  Surv Ophthalmol       Date:  2011 Nov-Dec       Impact factor: 6.048

2.  Treatment of choroid metastasis from lung adenocarcinoma with bevacizumab-containing chemotherapy: A case report.

Authors:  Kenichi Makabe; Koichi Kurishima; Toshihiro Shiozawa; Kunihiko Miyazaki; Gen Ohara; Katsunori Kagohashi; Hiroaki Satoh; Nobuyuki Hizawa
Journal:  Exp Ther Med       Date:  2015-11-25       Impact factor: 2.447

Review 3.  Lung cancer and eye metastases.

Authors:  Sofia Lampaki; Ioannis Kioumis; Georgia Pitsiou; George Lazaridis; Konstantinos Syrigos; Georgia Trakada; Stylianos Kakolyris; Konstantinos Zarogoulidis; Ioannis Mpoukovinas; Aggeliki Rapti; Paul Zarogoulidis
Journal:  Med Hypothesis Discov Innov Ophthalmol       Date:  2014

4.  Choroid metastases revealing primary clear cell adenocarcinoma of the lung effectively treated with cisplatin and pemetrexed: a case report.

Authors:  Yueh-Shih Chang; Ling Yeung; Liang-Che Chang; Jen-Seng Huang; Kun-Yun Yeh
Journal:  J Med Case Rep       Date:  2013-12-11

5.  Bilateral choroidal metastasis from non-small cell lung cancer.

Authors:  Tariq Namad; Jiang Wang; Annemarie Tilton; Nagla Abdel Karim
Journal:  Case Rep Oncol Med       Date:  2014-09-14

Review 6.  Choroidal metastases: origin, features, and therapy.

Authors:  Sruthi Arepalli; Swathi Kaliki; Carol L Shields
Journal:  Indian J Ophthalmol       Date:  2015-02       Impact factor: 1.848

7.  Lung squamous cell carcinoma with solitary ocular metastasis and its successful treatment with thoracic surgery and chemotherapy: an interesting and rare case report.

Authors:  Ye Guo; Xu Wang; Jun Xiao; Yinghui Xu; Yangyang Cai; Chao Sun; Kewei Ma
Journal:  BMC Cancer       Date:  2018-10-20       Impact factor: 4.430

  7 in total

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