OBJECTIVE: To determine the peak time of outbreak of Crimean-Congo haemorrhagic fever (CCHF) and to highlight the disease-specific areas in the Balochistan province of Pakistan. DESIGN: A hospital-based case-series study. PLACE AND DURATION: A five-year study was conducted by the Department of Pathology in collaboration with the Department of Medicine, Sandeman Provincial Teaching Hospital, Quetta, Balochistan, Pakistan, from 1 March 1997 to 28 February 2002. PATIENTS AND METHODS: A total of 135 cases were included in the study based on a high index of suspicion of CCHF. The mean age was 33.5+/-18.7 years. Two sets of blood samples were drawn on admission; one set was sent for urgent routine investigations while the other was sent to CDC, Atlanta, USA, for confirmation. RESULTS: The study showed that CCHF was more common between March and May and again, between August and October, depicting a bi-annual surge. Out of 135 suspected cases, 83 (61.4%) were confirmed to have CCHF and were given platelet concentrate and ribavirin. It ws observed that CCHF was more common in specific areas of the province. CONCLUSIONS: It is essential to raise the level of knowledge regarding CCHF, especially in disease-specific areas, focussing on the peak outbreak periods.
OBJECTIVE: To determine the peak time of outbreak of Crimean-Congo haemorrhagic fever (CCHF) and to highlight the disease-specific areas in the Balochistan province of Pakistan. DESIGN: A hospital-based case-series study. PLACE AND DURATION: A five-year study was conducted by the Department of Pathology in collaboration with the Department of Medicine, Sandeman Provincial Teaching Hospital, Quetta, Balochistan, Pakistan, from 1 March 1997 to 28 February 2002. PATIENTS AND METHODS: A total of 135 cases were included in the study based on a high index of suspicion of CCHF. The mean age was 33.5+/-18.7 years. Two sets of blood samples were drawn on admission; one set was sent for urgent routine investigations while the other was sent to CDC, Atlanta, USA, for confirmation. RESULTS: The study showed that CCHF was more common between March and May and again, between August and October, depicting a bi-annual surge. Out of 135 suspected cases, 83 (61.4%) were confirmed to have CCHF and were given platelet concentrate and ribavirin. It ws observed that CCHF was more common in specific areas of the province. CONCLUSIONS: It is essential to raise the level of knowledge regarding CCHF, especially in disease-specific areas, focussing on the peak outbreak periods.
Authors: Paul W Blair; Jens H Kuhn; David B Pecor; Dmitry A Apanaskevich; Mark G Kortepeter; Anthony P Cardile; Aileen Polanco Ramos; Maryam Keshtkar-Jahromi Journal: Am J Trop Med Hyg Date: 2019-01 Impact factor: 2.345
Authors: Samuel Johnson; Nicholas Henschke; Nicola Maayan; Inga Mills; Brian S Buckley; Artemisia Kakourou; Rachel Marshall Journal: Cochrane Database Syst Rev Date: 2018-06-05