Literature DB >> 15694184

Update on MALT lymphomas.

Peter G Isaacson1.   

Abstract

Gastric mucosa associated lymphoid tissue (MALT) lymphoma is a histologically distinct tumour derived from MALT acquired as a result of Helicobacter pylori infection. Eradication of H. pylori causes clinical regression of the lymphoma in 75% of cases. In seeking to identify those cases resistant to this therapy, and in the interests of further understanding the biology of MALT lymphoma, genetic alterations of MALT lymphomas have been investigated. Three translocations, t(11;18)(q21;q21), t(1;14)(p22;q32) and t(14;18)(q32;q21) are specifically associated with MALT lymphoma and the genes involved have been identified. T(11;18) results in a chimeric fusion between the API2 and MALT1 genes and is specifically associated with gastric MALT lymphomas that do not respond to eradication of H. pylori. T(1;14) and t(14;18) deregulate BCL10 and MALT1 expression, respectively. These three chromosomal translocations that involve different genes appear to share common oncogenic properties by targeting the same nuclear factor kappa B (NF kappa B) oncogenic pathway.

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Year:  2005        PMID： 15694184     DOI： 10.1016/j.beha.2004.08.003

Source DB:  PubMed          Journal:  Best Pract Res Clin Haematol        ISSN： 1521-6926            Impact factor:   3.020


  24 in total

1.  From lymphocytic interstitial pneumonia to MALT lymphoma of lung: a case report with a 5-year diagnostic dilemma.

Authors:  Wei Wu; Jing Zhou; Li-Gai Di; Hui Chen
Journal:  Int J Clin Exp Pathol       Date:  2015-08-01

2.  A case of primary hepatic mucosa-associated lymphoid tissue lymphoma incidentally found in the sustained virological response state of chronic hepatitis C: review of the literature of this rare disease.

Authors:  Tadahito Yasuda; Shigeki Nakagawa; Katsunori Imai; Hirohisa Okabe; Hiromitsu Hayashi; Yo-Ichi Yamashita; Akira Chikamoto; Kazutaka Ozono; Yoshiki Mikami; Hideo Baba
Journal:  Int Cancer Conf J       Date:  2020-01-03

3.  Multiple mucosa-associated lymphoid tissue organs involving marginal zone B cell lymphoma: organ-specific relationships and the prognostic factors. Consortium for improving survival of lymphoma study.

Authors:  Sung Yong Oh; Won Seog Kim; Jin Seok Kim; Seok Jin Kim; Suee Lee; Dae Ho Lee; Jong-Ho Won; In Gyu Hwang; Min Kyoung Kim; Soon Il Lee; Yee Soo Chae; Deok-Hwan Yang; Hye Jin Kang; Chul Won Choi; Jinny Park; Hyo Jung Kim; Jung Hye Kwon; Ho Sup Lee; Gyeong-Won Lee; Hyeon Seok Eom; Jae-Yong Kwak; Won Sik Lee; Cheolwon Suh; Hyo-Jin Kim
Journal:  Int J Hematol       Date:  2010-09-14       Impact factor: 2.490

4.  Gastric low-grade mucosal-associated lymphoid tissue-lymphoma: Helicobacter pylori and beyond.

Authors:  Angelo Zullo; Cesare Hassan; Francesca Cristofari; Francesco Perri; Sergio Morini
Journal:  World J Gastrointest Oncol       Date:  2010-04-15

Review 5.  Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death.

Authors:  Domagoj Vucic; Vishva M Dixit; Ingrid E Wertz
Journal:  Nat Rev Mol Cell Biol       Date:  2011-06-23       Impact factor: 94.444

6.  Hepatitis C and non-Hodgkin lymphoma among 4784 cases and 6269 controls from the International Lymphoma Epidemiology Consortium.

Authors:  Silvia de Sanjose; Yolanda Benavente; Claire M Vajdic; Eric A Engels; Lindsay M Morton; Paige M Bracci; John J Spinelli; Tongzhang Zheng; Yawei Zhang; Silvia Franceschi; Renato Talamini; Elizabeth A Holly; Andrew E Grulich; James R Cerhan; Patricia Hartge; Wendy Cozen; Paolo Boffetta; Paul Brennan; Marc Maynadié; Pierluigi Cocco; Ramon Bosch; Lenka Foretova; Anthony Staines; Nikolaus Becker; Alexandra Nieters
Journal:  Clin Gastroenterol Hepatol       Date:  2008-04       Impact factor: 11.382

Review 7.  Role of Helicobacter pylori in gastric mucosa-associated lymphoid tissue lymphomas.

Authors:  Marta-Isabel Pereira; José Augusto Medeiros
Journal:  World J Gastroenterol       Date:  2014-01-21       Impact factor: 5.742

8.  Is there role of additional chemotherapy after definitive local treatment for stage I/II marginal zone lymphoma?: Consortium for Improving Survival of Lymphoma (CISL) study.

Authors:  Myeong Seok Koh; Won Seog Kim; Seok Jin Kim; Sung Yong Oh; Dok Hyun Yoon; Soon Il Lee; Junshik Hong; Moo Kon Song; Ho-Jin Shin; Jung Hye Kwon; Hyo Jung Kim; Yong Rok Do; Cheolwon Suh; Hyo Jin Kim
Journal:  Int J Hematol       Date:  2015-07-26       Impact factor: 2.490

9.  Phase II study of gemcitabine for treatment of patients with advanced stage marginal zone B-cell lymphoma: Consortium for Improving Survival of Lymphoma (CISL) trial.

Authors:  Sung Yong Oh; Won Seog Kim; Dae Ho Lee; Seok Jin Kim; Sung Hyun Kim; Baek Yeol Ryoo; Hye Jin Kang; Young Jin Choi; Joo Seop Chung; Hyo Jung Kim; Cheolwon Suh
Journal:  Invest New Drugs       Date:  2009-05-07       Impact factor: 3.850

Review 10.  Clinical aspects of malt lymphomas.

Authors:  Christina Kalpadakis; Gerassimos A Pangalis; Theodoros P Vassilakopoulos; Stavroula Kyriakaki; Xanthi Yiakoumis; Sotirios Sachanas; Maria Moschogiannis; Pantelis Tsirkinidis; Penelope Korkolopoulou; Helen A Papadaki; Maria K Angelopoulou
Journal:  Curr Hematol Malig Rep       Date:  2014-09       Impact factor: 3.952
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