Literature DB >> 15691974

Purification and cDNA cloning of NADPH-dependent aldoketoreductase, involved in asymmetric reduction of methyl 4-bromo-3-oxobutyrate, from Penicillium citrinum IFO4631.

Hiroyuki Asako1, Ryuhei Wakita, Kenji Matsumura, Masatoshi Shimizu, Jun Sakai, Nobuya Itoh.   

Abstract

Penicillium citrinum was found to catalyze the reduction of methyl 4-bromo-3-oxobutyrate to methyl (S)-4-bromo-3-hydroxybutyrate [(S)-BHBM] with high optical purity. From the strain, a cDNA clone encoding a novel NADPH-dependent alkyl 4-halo-3-oxobutyrate reductase (KER) was isolated. Escherichia coli cells overexpressing KER produced (S)-BHBM in the presence of an NADPH-regeneration system.

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Year:  2005        PMID： 15691974      PMCID： PMC546806          DOI： 10.1128/AEM.71.2.1101-1104.2005

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  12 in total

1.  Stereoselective reduction of ethyl 4-chloro-3-oxobutanoate by fungi.

Authors:  Y Saratani; E Uheda; H Yamamoto; A Nishimura; F Yoshizako
Journal:  Biosci Biotechnol Biochem       Date:  2001-07       Impact factor: 2.043

2.  Androgen-dependent protein from mouse vas deferens. cDNA cloning and protein homology with the aldo-keto reductase superfamily.

Authors:  E A Pailhoux; A Martinez; G M Veyssiere; C G Jean
Journal:  J Biol Chem       Date:  1990-11-15       Impact factor: 5.157

Review 3.  Comparative anatomy of the aldo-keto reductase superfamily.

Authors:  J M Jez; M J Bennett; B P Schlegel; M Lewis; T M Penning
Journal:  Biochem J       Date:  1997-09-15       Impact factor: 3.857

4.  Transcriptional control by galactose of a yeast gene encoding a protein homologous to mammalian aldo/keto reductases.

Authors:  V Magdolen; U Oechsner; P Trommler; W Bandlow
Journal:  Gene       Date:  1990-05-31       Impact factor: 3.688

5.  Cloning of the aldehyde reductase gene from a red yeast, Sporobolomyces salmonicolor, and characterization of the gene and its product.

Authors:  K Kita; K Matsuzaki; T Hashimoto; H Yanase; N Kato; M C Chung; M Kataoka; S Shimizu
Journal:  Appl Environ Microbiol       Date:  1996-07       Impact factor: 4.792

6.  Synthesis of optically active ethyl 4-chloro-3-hydroxybutanoate by microbial reduction.

Authors:  Y Yasohara; N Kizaki; J Hasegawa; S Takahashi; M Wada; M Kataoka; S Shimizu
Journal:  Appl Microbiol Biotechnol       Date:  1999-06       Impact factor: 4.813

7.  Amino acid sequence and characterization of aldo-keto reductase from bakers' yeast.

Authors:  K Nakamura; S Kondo; Y Kawai; N Nakajima; A Ohno
Journal:  Biosci Biotechnol Biochem       Date:  1997-02       Impact factor: 2.043

8.  The mystery of the trichothecene 3-O-acetyltransferase gene. Analysis of the region around Tri101 and characterization of its homologue from Fusarium sporotrichioides.

Authors:  M Kimura; G Matsumoto; Y Shingu; K Yoneyama; I Yamaguchi
Journal:  FEBS Lett       Date:  1998-09-18       Impact factor: 4.124

9.  Glycerol dehydrogenase, encoded by gldB is essential for osmotolerance in Aspergillus nidulans.

Authors:  Ronald P de Vries; Simon J Flitter; Peter J I van de Vondervoort; Marie-Kim Chaveroche; Thierry Fontaine; Sabine Fillinger; George J G Ruijter; Christophe d'Enfert; Jaap Visser
Journal:  Mol Microbiol       Date:  2003-07       Impact factor: 3.501

10.  Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110.

Authors:  I Tarle; D W Borhani; D K Wilson; F A Quiocho; J M Petrash
Journal:  J Biol Chem       Date:  1993-12-05       Impact factor: 5.157
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  1 in total

1.  Gene mining, codon optimization and analysis of binding mechanism of an aldo-keto reductase with high activity, better substrate specificity and excellent solvent tolerance.

Authors:  Wei Jiang; Xiaoli Fu; Weiliang Wu
Journal:  PLoS One       Date:  2021-12-02       Impact factor: 3.240
  1 in total

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