Literature DB >> 15691757

Costal-2: a scaffold for kinases mediates Hedgehog signaling.

Shunsuke Ishii1.   

Abstract

Drosophila genetics has identified several components of the Hedgehog signaling pathway, but the mechanism by which they act remains elusive. In this issue of Developmental Cell, a report by Zhang et al. provides evidence that the kinesin-related protein Costal-2 forms a multi-component scaffold that mediates Hedgehog signaling.

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Year:  2005        PMID: 15691757     DOI: 10.1016/j.devcel.2005.01.004

Source DB:  PubMed          Journal:  Dev Cell        ISSN: 1534-5807            Impact factor:   12.270


  2 in total

Review 1.  Unconventional functions of microtubule motors.

Authors:  Virgil Muresan; Zoia Muresan
Journal:  Arch Biochem Biophys       Date:  2012-01-28       Impact factor: 4.013

2.  Hedgehog signaling downregulates suppressor of fused through the HIB/SPOP-Crn axis in Drosophila.

Authors:  Chen Liu; Zizhang Zhou; Xia Yao; Ping Chen; Man Sun; Miya Su; Cunjie Chang; Jun Yan; Jin Jiang; Qing Zhang
Journal:  Cell Res       Date:  2014-03-07       Impact factor: 25.617

  2 in total

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