Literature DB >> 15691246

Metered dose inhalers: a need for dose counters.

Shaun Holt1, Avrille Holt, Mark Weatherall, Matthew Masoli, Richard Beasley.   

Abstract

OBJECTIVES: This study investigated the ability of patients to assess when a metered dose inhaler (MDI) is empty.
METHODOLOGY: A total of 17 patients assessed, by shaking, the number of doses remaining in a salbutamol MDI that had been partially emptied. Another 100 patients were asked to collect all salbutamol MDIs they considered to be empty and would have thrown away. These MDI canisters were weighed and the number of doses that had been used was estimated.
RESULTS: Using the 'shaking method', patients overestimated the amount remaining by around 40 doses. The mean number of doses delivered from an MDI labelled to contain 200 doses before it was discarded was 224 (range, 155-289).
CONCLUSIONS: These findings confirm that patients are unable to determine when an MDI should be discarded, resulting in insufficient drug delivery at the end of the life of an MDI for the majority of patients, and wastage of the drug for others.

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Year:  2005        PMID: 15691246     DOI: 10.1111/j.1440-1843.2005.00629.x

Source DB:  PubMed          Journal:  Respirology        ISSN: 1323-7799            Impact factor:   6.424


  5 in total

Review 1.  Advances in metered dose inhaler technology: hardware development.

Authors:  Stephen W Stein; Poonam Sheth; P David Hodson; Paul B Myrdal
Journal:  AAPS PharmSciTech       Date:  2013-12-20       Impact factor: 3.246

2.  Emergency department visits for acute asthma by adults who ran out of their inhaled medications.

Authors:  Kohei Hasegawa; Barry E Brenner; Sunday Clark; Carlos A Camargo
Journal:  Allergy Asthma Proc       Date:  2014 May-Jun       Impact factor: 2.587

Review 3.  Improving asthma management: the case for mandatory inclusion of dose counters on all rescue bronchodilators.

Authors:  Jill B Conner; Philip O Buck
Journal:  J Asthma       Date:  2013-04-29       Impact factor: 2.515

4.  Real-world health care utilization in asthma patients using albuterol sulfate inhalation aerosol (ProAir ® HFA) with and without integrated dose counters.

Authors:  Edward M Kerwin; Thomas J Ferro; Rinat Ariely; Debra E Irwin; Ruchir Parikh
Journal:  J Asthma Allergy       Date:  2017-05-17

5.  Achieving good adherence to inhaled corticosteroids after weighing canisters of asthmatic children.

Authors:  Wantida Chuenjit; Vorapan Engchuan; Araya Yuenyongviwat; Pasuree Sangsupawanich
Journal:  F1000Res       Date:  2017-03-14
  5 in total

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