Literature DB >> 15690603

A walk-through of the yeast mating pheromone response pathway.

Lee Bardwell1.   

Abstract

The intracellular signal transduction pathway by which the yeast Saccharomyces cerevisiae responds to the presence of peptide mating pheromone in its surroundings is one of the best understood signaling pathways in eukaryotes, yet continues to generate new surprises and insights. In this review, we take a brief walk down the pathway, focusing on how the signal is transmitted from the cell-surface receptor-coupled G protein, via a MAP kinase cascade, to the nucleus.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 15690603      PMCID： PMC3017506          DOI： 10.1016/j.peptides.2004.10.002

Source DB:  PubMed          Journal:  Peptides        ISSN： 0196-9781            Impact factor:   3.750


  157 in total

1.  Pheromone-dependent G1 cell cycle arrest requires Far1 phosphorylation, but may not involve inhibition of Cdc28-Cln2 kinase, in vivo.

Authors:  A Gartner; A Jovanović; D I Jeoung; S Bourlat; F R Cross; G Ammerer
Journal:  Mol Cell Biol       Date:  1998-07       Impact factor: 4.272

Review 2.  Signal transduction through MAP kinase cascades.

Authors:  T S Lewis; P S Shapiro; N G Ahn
Journal:  Adv Cancer Res       Date:  1998       Impact factor: 6.242

3.  The mating-specific G(alpha) protein of Saccharomyces cerevisiae downregulates the mating signal by a mechanism that is dependent on pheromone and independent of G(beta)(gamma) sequestration.

Authors:  H F Stratton; J Zhou; S I Reed; D E Stone
Journal:  Mol Cell Biol       Date:  1996-11       Impact factor: 4.272

4.  Cln3-associated kinase activity in Saccharomyces cerevisiae is regulated by the mating factor pathway.

Authors:  D I Jeoung; L J Oehlen; F R Cross
Journal:  Mol Cell Biol       Date:  1998-01       Impact factor: 4.272

5.  MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation.

Authors:  H D Madhani; C A Styles; G R Fink
Journal:  Cell       Date:  1997-11-28       Impact factor: 41.582

6.  Sst2 is a GTPase-activating protein for Gpa1: purification and characterization of a cognate RGS-Galpha protein pair in yeast.

Authors:  D M Apanovitch; K C Slep; P B Sigler; H G Dohlman
Journal:  Biochemistry       Date:  1998-04-07       Impact factor: 3.162

7.  Functional binding between Gbeta and the LIM domain of Ste5 is required to activate the MEKK Ste11.

Authors:  Y Feng; L Y Song; E Kincaid; S K Mahanty; E A Elion
Journal:  Curr Biol       Date:  1998-02-26       Impact factor: 10.834

8.  Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases.

Authors:  T Leeuw; C Wu; J D Schrag; M Whiteway; D Y Thomas; E Leberer
Journal:  Nature       Date:  1998-01-08       Impact factor: 49.962

9.  A role for the yeast actin cytoskeleton in pheromone receptor clustering and signalling.

Authors:  K R Ayscough; D G Drubin
Journal:  Curr Biol       Date:  1998 Jul 30-Aug 13       Impact factor: 10.834

10.  Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization.

Authors:  L Hicke; B Zanolari; H Riezman
Journal:  J Cell Biol       Date:  1998-04-20       Impact factor: 10.539
View more
  138 in total

1.  Possible additional roles in mating for Ustilago maydis Rho1 and 14-3-3 homologues.

Authors:  Cau D Pham; Michael H Perlin
Journal:  Commun Integr Biol       Date:  2010-01

2.  Roles for receptors, pheromones, G proteins, and mating type genes during sexual reproduction in Neurospora crassa.

Authors:  Hyojeong Kim; Sara J Wright; Gyungsoon Park; Shouqiang Ouyang; Svetlana Krystofova; Katherine A Borkovich
Journal:  Genetics       Date:  2012-01-31       Impact factor: 4.562

3.  Identifying sources of variation and the flow of information in biochemical networks.

Authors:  Clive G Bowsher; Peter S Swain
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-23       Impact factor: 11.205

4.  Information flow in interaction networks II: channels, path lengths, and potentials.

Authors:  Aleksandar Stojmirović; Yi-Kuo Yu
Journal:  J Comput Biol       Date:  2012-03-12       Impact factor: 1.479

5.  CRISPR-addressable yeast strains with applications in human G protein-coupled receptor profiling and synthetic biology.

Authors:  Jacob B Rowe; Geoffrey J Taghon; Nicholas J Kapolka; William M Morgan; Daniel G Isom
Journal:  J Biol Chem       Date:  2020-05-01       Impact factor: 5.157

6.  Mitogen-activated protein kinases with distinct requirements for Ste5 scaffolding influence signaling specificity in Saccharomyces cerevisiae.

Authors:  Laura J Flatauer; Sheena F Zadeh; Lee Bardwell
Journal:  Mol Cell Biol       Date:  2005-03       Impact factor: 4.272

7.  Regulation of mating and filamentation genes by two distinct Ste12 complexes in Saccharomyces cerevisiae.

Authors:  Song Chou; Shelley Lane; Haoping Liu
Journal:  Mol Cell Biol       Date:  2006-07       Impact factor: 4.272

8.  G-protein signaling: a new branch in an old pathway.

Authors:  Lee Bardwell
Journal:  Curr Biol       Date:  2006-10-10       Impact factor: 10.834

9.  Mathematical models of specificity in cell signaling.

Authors:  Lee Bardwell; Xiufen Zou; Qing Nie; Natalia L Komarova
Journal:  Biophys J       Date:  2007-02-26       Impact factor: 4.033

10.  CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5.

Authors:  María Victoria Repetto; Matthew J Winters; Alan Bush; Wolfgang Reiter; David Maria Hollenstein; Gustav Ammerer; Peter M Pryciak; Alejandro Colman-Lerner
Journal:  Mol Cell       Date:  2018-03-15       Impact factor: 17.970
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.