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Literature DB >> 15690073

Paget disease of bone.

Abstract

Paget disease of bone (PD) is characterized by excessive bone resorption in focal areas followed by abundant new bone formation, with eventual replacement of the normal bone marrow by vascular and fibrous tissue. The etiology of PD is not well understood, but one PD-linked gene and several other susceptibility loci have been identified, and paramyxoviral gene products have been detected in pagetic osteoclasts. In this review, the pathophysiology of PD and evidence for both a genetic and a viral etiology for PD will be discussed.

Entities: Disease

Mesh：

Year: 2005 PMID： 15690073 PMCID： PMC546434 DOI： 10.1172/JCI24281

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

107 in total

1. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts.

Authors: Hiroshi Takayanagi; Sunhwa Kim; Takako Koga; Hiroshi Nishina; Masashi Isshiki; Hiroki Yoshida; Akio Saiura; Miho Isobe; Taeko Yokochi; Jun-ichiro Inoue; Erwin F Wagner; Tak W Mak; Tatsuhiko Kodama; Tadatsugu Taniguchi
Journal: Dev Cell Date: 2002-12 Impact factor: 12.270

2. Dogs and Paget's disease.

Authors: D C Anderson; J B O'Driscoll
Journal: Lancet Date: 1986-01-04 Impact factor: 79.321

3. Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene.

Authors: N Kim; P R Odgren; D K Kim; S C Marks; Y Choi
Journal: Proc Natl Acad Sci U S A Date: 2000-09-26 Impact factor: 11.205

Review 4. Mechanisms balancing skeletal matrix synthesis and degradation.

Authors: Harry C Blair; Mone Zaidi; Paul H Schlesinger
Journal: Biochem J Date: 2002-06-01 Impact factor: 3.857

5. Measles virus nucleocapsid transcript expression is not restricted to the osteoclast lineage in patients with Paget's disease of bone.

Authors: S V Reddy; C Menaa; F R Singer; T Cundy; J Cornish; M P Whyte; G D Roodman
Journal: Exp Hematol Date: 1999-10 Impact factor: 3.084

6. Use of an in vivo model to determine the effects of interleukin-1 on cells at different stages in the osteoclast lineage.

Authors: H L Uy; M Dallas; J W Calland; B F Boyce; G R Mundy; G D Roodman
Journal: J Bone Miner Res Date: 1995-02 Impact factor: 6.741

7. Absence of paramyxovirus RNA in cultures of pagetic bone cells and in pagetic bone.

Authors: M A Birch; W Taylor; W D Fraser; S H Ralston; C A Hart; J A Gallagher
Journal: J Bone Miner Res Date: 1994-01 Impact factor: 6.741

8. Role of TAFII-17, a VDR binding protein, in the increased osteoclast formation in Paget's Disease.

Authors: Noriyoshi Kurihara; Sakamuri V Reddy; Norie Araki; Seiichi Ishizuka; Keiichi Ozono; Jillian Cornish; Tim Cundy; Frederick R Singer; G David Roodman
Journal: J Bone Miner Res Date: 2004-03-15 Impact factor: 6.741

9. Frequency and characteristics of familial aggregation of Paget's disease of bone.

Authors: A A Morales-Piga; J S Rey-Rey; J Corres-González; J M García-Sagredo; G López-Abente
Journal: J Bone Miner Res Date: 1995-04 Impact factor: 6.741

10. Canine distemper virus localised in bone cells of patients with Paget's disease.

Authors: M T Gordon; D C Anderson; P T Sharpe
Journal: Bone Date: 1991 Impact factor: 4.398

87 in total

Review 1. New knowledge on critical osteoclast formation and activation pathways from study of rare genetic diseases of osteoclasts: focus on the RANK/RANKL axis.

Authors: J C Crockett; D J Mellis; D I Scott; M H Helfrich
Journal: Osteoporos Int Date: 2010-05-11 Impact factor: 4.507

2. Assay of in vitro osteoclast activity on dentine, and synthetic calcium phosphate bone substitutes.

Authors: Zahi Badran; Paul Pilet; Elise Verron; Jean-Michel Bouler; Pierre Weiss; Gaël Grimandi; Jérôme Guicheux; Assem Soueidan
Journal: J Mater Sci Mater Med Date: 2011-12-22 Impact factor: 3.896

3. TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation.

Authors: Kenta Maruyama; Tatsukata Kawagoe; Takeshi Kondo; Shizuo Akira; Osamu Takeuchi
Journal: J Biol Chem Date: 2012-07-06 Impact factor: 5.157

4. The majority of the genetic risk for Paget's disease of bone is explained by genetic variants close to the CSF1, OPTN, TM7SF4, and TNFRSF11A genes.

Authors: Pui Yan Jenny Chung; Greet Beyens; Steven Boonen; Socrates Papapoulos; Piet Geusens; Marcel Karperien; Filip Vanhoenacker; Leon Verbruggen; Erik Fransen; Jan Van Offel; Stefan Goemaere; Hans-Georg Zmierczak; René Westhovens; Jean-Pierre Devogelaer; Wim Van Hul
Journal: Hum Genet Date: 2010-09-14 Impact factor: 4.132

5. Contributions of the measles virus nucleocapsid gene and the SQSTM1/p62(P392L) mutation to Paget's disease.

Authors: Noriyoshi Kurihara; Yuko Hiruma; Kei Yamana; Laëtitia Michou; Côme Rousseau; Jean Morissette; Deborah L Galson; Jumpei Teramachi; Hua Zhou; David W Dempster; Jolene J Windle; Jacques P Brown; G David Roodman
Journal: Cell Metab Date: 2011-01-05 Impact factor: 27.287

6. Osteoclast inhibitory peptide-1 (OIP-1) inhibits measles virus nucleocapsid protein stimulated osteoclast formation/activity.

Authors: Srinivasan Shanmugarajan; Rimon F Youssef; Parmita Pati; William L Ries; D Sudhaker Rao; Sakamuri V Reddy
Journal: J Cell Biochem Date: 2008-07-01 Impact factor: 4.429

Review 10. The osteoclast--what's new?

Authors: Nicolas A Athanasou
Journal: Skeletal Radiol Date: 2011-08-17 Impact factor: 2.199