Literature DB >> 15689573

Fibroblast growth factor signaling during early vertebrate development.

Ralph T Böttcher1, Christof Niehrs.   

Abstract

Fibroblast growth factors (FGFs) have been implicated in diverse cellular processes including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, and proliferation. This review presents our current understanding on the roles of FGF signaling, the pathways employed, and its regulation. We focus on FGF signaling during early embryonic processes in vertebrates, such as induction and patterning of the three germ layers as well as its function in the control of morphogenetic movements.

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Year:  2005        PMID： 15689573     DOI： 10.1210/er.2003-0040

Source DB:  PubMed          Journal:  Endocr Rev        ISSN： 0163-769X            Impact factor:   19.871


  178 in total

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