Literature DB >> 15687878

Military importance of diarrhea: lessons from the Middle East.

John W Sanders1, Shannon D Putnam, Mark S Riddle, David R Tribble.   

Abstract

PURPOSE OF REVIEW: Historically, diarrhea has been one of the most important diseases encountered during military operations. With more than 140,000 US military personnel currently deployed to the Middle East in support of the global war on terror, it is important for health care providers and planners to be aware of the incidence and potential impact of diarrheal disease in that region. RECENT
FINDINGS: Recently published data from mid-deployment surveys assessing the incidence and clinical impact of diarrhea on troops deployed to Iraq and Afghanistan have been updated and presented along with a review of the recent literature concerning diarrheal pathogens of military concern in the Middle East. Of 4348 volunteers, 76% reported at least one diarrhea episode during their deployment and more than half reported multiple episodes. In 45% of subjects, diarrhea resulted in decreased job performance for a median of 3 days. Diarrhea resulted in 62% of subjects seeking medical care at least once, and 31% required intravenous rehydration. In 17% of subjects, diarrhea resulted in confinement to bed for a median of 2 days, causing an estimated 3.7 days (Poisson 95% CI, 3.4 to 4.0 days) of complete work loss per 100 person-months.
SUMMARY: Despite modern preventive medicine efforts, diarrhea rates remain high, and the impact of illness remains a threat to military efficiency. Novel enteric disease research programs designed to decrease the impact of diarrhea on the military mission are needed. The development of enteric vaccines and appropriate treatment regimens remain a top priority.

Entities:  

Mesh:

Year:  2005        PMID: 15687878

Source DB:  PubMed          Journal:  Curr Opin Gastroenterol        ISSN: 0267-1379            Impact factor:   3.287


  25 in total

1.  Global Infectious Disease Surveillance at DoD Overseas Laboratories, 1999-2007.

Authors:  J Jeremy Sueker; Jean-Paul Chretien; Joel C Gaydos; Kevin L Russell
Journal:  Am J Trop Med Hyg       Date:  2010-01       Impact factor: 2.345

2.  Multiepitope fusion antigen induces broadly protective antibodies that prevent adherence of Escherichia coli strains expressing colonization factor antigen I (CFA/I), CFA/II, and CFA/IV.

Authors:  Xiaosai Ruan; David E Knudsen; Katie M Wollenberg; David A Sack; Weiping Zhang
Journal:  Clin Vaccine Immunol       Date:  2013-12-18

3.  Vaccines against gastroenteritis, current progress and challenges.

Authors:  Hyesuk Seo; Qiangde Duan; Weiping Zhang
Journal:  Gut Microbes       Date:  2020-06-18

4.  Gastrointestinal illnesses among French forces deployed to Djibouti: French military health surveillance, 2005-2009.

Authors:  Lénaïck Ollivier; Christophe Decam; Vincent Pommier de Santi; Houssein Y Darar; Aïssata Dia; Remington L Nevin; Olivier Romand; Jacques Bougère; Xavier Deparis; Jean-Paul Boutin
Journal:  Am J Trop Med Hyg       Date:  2010-10       Impact factor: 2.345

5.  A prospective study of acute diarrhea in a cohort of United States military personnel on deployment to the Multinational Force and Observers, Sinai, Egypt.

Authors:  Mark S Riddle; David M Rockabrand; Carey Schlett; Marshall R Monteville; Robert W Frenck; Marcy Romine; Salwa F Ahmed; John W Sanders
Journal:  Am J Trop Med Hyg       Date:  2011-01       Impact factor: 2.345

6.  Enterotoxigenic Escherichia coli Adhesin-Toxoid Multiepitope Fusion Antigen CFA/I/II/IV-3xSTaN12S-mnLTG192G/L211A-Derived Antibodies Inhibit Adherence of Seven Adhesins, Neutralize Enterotoxicity of LT and STa Toxins, and Protect Piglets against Diarrhea.

Authors:  Rahul Nandre; Xiaosai Ruan; Ti Lu; Qiangde Duan; David Sack; Weiping Zhang
Journal:  Infect Immun       Date:  2018-02-20       Impact factor: 3.441

7.  The epidemiology of infectious gastroenteritis related reactive arthritis in U.S. military personnel: a case-control study.

Authors:  Jennifer A Curry; Mark S Riddle; Robert P Gormley; David R Tribble; Chad K Porter
Journal:  BMC Infect Dis       Date:  2010-09-13       Impact factor: 3.090

8.  Characterization of heat-stable (STa) toxoids of enterotoxigenic Escherichia coli fused to double mutant heat-labile toxin peptide in inducing neutralizing Anti-STa antibodies.

Authors:  Xiaosai Ruan; Donald C Robertson; James P Nataro; John D Clements; Weiping Zhang
Journal:  Infect Immun       Date:  2014-02-18       Impact factor: 3.441

9.  Past trends and current status of self-reported incidence and impact of disease and nonbattle injury in military operations in Southwest Asia and the Middle East.

Authors:  Mark S Riddle; David R Tribble; Shannon D Putnam; Manal Mostafa; Theodore R Brown; Andrew Letizia; Adam W Armstrong; John W Sanders
Journal:  Am J Public Health       Date:  2008-10-15       Impact factor: 9.308

10.  Antibiotic Therapy for Acute Watery Diarrhea and Dysentery.

Authors:  David R Tribble
Journal:  Mil Med       Date:  2017-09       Impact factor: 1.437

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